Chemically based vascular occlusion device deployment

1. A vascular occlusion deployment system, comprising:

a deployment unit comprising a pusher having a proximal end portion and a distal end portion with a distal opening,

the distal opening sized and shaped to temporarily accept a protruding portion of a vascular occlusion device;

an expandable reaction chamber located within the pusher proximal the distal opening of the pusher, the expandable chamber expandable in a direction toward the distal end portion of the pusher;

said reaction chamber including a first sub-chamber and a second sub-chamber separated by a heat dissolvable membrane;

a first reactant located within the first sub-chamber and a second reactant located within the second sub-chamber;

a heating generating system capable of dissolving the heat dissolvable element to allow said first reactant and second reactant to mix, forming a product that expands in the direction of the distal opening; and

said expanding product applying a force to the reaction chamber causing a portion of the reaction chamber to expand in the direction of the distal opening, said portion of the reaction chamber capable of contacting a protruding portion of a vascular occlusion device within the distal opening and pushing the protruding portion out of the distal opening, thereby deploying the vascular occlusion device.

2. The deployment system of claim 1 , wherein the heat dissolvable membrane is of a material that comprises a polyolefin.

3. The deployment system of claim 1 , wherein the heat dissolvable membrane degrades at a temperature above human body temperature.

4. The deployment system of claim 3 , wherein said temperature is at least about 40 degrees C.

5. The deployment system of claim 1 , wherein the first reactant comprises a mixture of cyanoacrylate monomer and ethanol, and the second reactant comprises mixture of ethanol and N,N-Dimethyl-p-toluidine.

6. The deployment system of claim 1 , wherein the product comprises a polycyanoacrylate foam.

7. The deployment system of claim 1 , wherein the reaction chamber comprises a polymeric material.

8. The deployment system of claim 1 , wherein the heat generating system comprises an electrical resistance heating coil connected to a power source via electrical leads.

9. The deployment system of claim 1 , wherein the vascular occlusion device is an embolic coil.

10. The deployment system of claim 1 , wherein the first sub-chamber and second sub-chamber are discrete sections.

11. A method for deployment of a vascular occlusion device at a preselected location within the vasculature of a patient, comprising:

providing a deployment unit comprising a pusher member having a distal end opening and a reaction chamber proximal thereof, said chamber including a first sub-chamber and a second sub-chamber separated by a heat dissolvable membrane, a first reactant housed in said first sub-chamber and a second reactant housed in the second sub-chamber;

removably disposing a vascular occlusion device having a portion protruding into the distal end opening of the lumen;

using the deployment unit to place the vascular occlusion device at a preselected location within the vasculature of a patient;

dissolving the heat dissolving membrane to cause the first reactant and the second reactant to react within the chamber, said reactants producing a product which has a larger volume than the reactants; and

directing the expanding product toward the distal end opening to remove the protruding portion from the distal end opening of the lumen, thereby deploying the vascular occlusion device.

12. The method according to claim 11 , wherein said dissolving the heat dissolving membrane comprises dissolving the heat dissolving membrane with an electrical resistance heating coil.

13. The method according to claim 11 , wherein said first reactant comprises a mixture of cyanoacrylate monomer and ethanol, and the second reactant comprises mixture of ethanol and N,N-Dimethyl-p-toluidine.