IP Library Granted Patent US 7,620,144
Granted Patent B2
US 7,620,144 · App. 11/478,047 · Granted Nov 17, 2009

Parallel stereovision geometry in image-guided radiosurgery

Assignee: Accuray Incorporated
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Quick Facts
Patent No.
US 7,620,144
App. No.
11/478,047
Filed
Jun 28, 2006
Granted
Nov 17, 2009
Kind
B2
Art Unit
2882
USPC
378/41
Abstract

A method and apparatus in an image-guided radiation treatment system for determining an in-treatment 3-D position of a patient and for registering the 3-D in-treatment position of the patient with a pre-treatment 3-D scan of the patient.

Claims (60)

1. A method in an image-guided radiation treatment system, comprising:

imaging a 3-D feature in an imaged volume with two or more in-treatment imaging X-ray sources having substantially parallel imaging axes, wherein imaging the 3-D feature comprises:

generating a first X-ray image of the imaged volume comprising a first image feature corresponding to the 3-D feature within the imaged volume; and

generating a second X-ray image substantially parallel to the first X-ray image, comprising a second image feature corresponding to the 3-D feature within the imaged volume, wherein the second image feature is substantially similar to the first image feature; and

locating the 3-D feature within the imaged volume.

2. The method of claim 1 , further comprising tracking the 3-D feature within the imaged volume by registering the 3-D feature with a 3-D pre-treatment volume study of the imaged volume.

3. The method of claim 1 , wherein locating the 3-D feature comprises:

matching the first image feature with the second image feature to obtain a pair of matched image features; and

determining a location of the 3-D feature within the imaged volume from planar coordinates of the pair of matched image features.

4. The method of claim 1 , wherein the first image feature in the first X-ray image comprises a first plurality of image points and the second image feature in the second X-ray image, substantially similar to the first image feature, comprises a second plurality of image points, and wherein matching the image features comprises computing a similarity measure between the first image feature and the second image feature and matching the first plurality of image points with the second plurality of image points in a plurality of conjugate pairs of image points.

5. The method of claim 4 , wherein determining the location of the 3-D feature within the imaged volume comprises mapping the plurality of conjugate pairs of image points to the plurality of feature points of the 3-D feature within the imaged volume.

6. The method of claim 1 , wherein the 3-D feature within the imaged volume comprise one of a fiducial marker, a curved edge, a corner and an endpoint.

7. A method in an image-guided radiation treatment system, comprising:

imaging a 3-D feature in an imaged volume with two or more in-treatment imaging X-ray sources having substantially parallel imaging axes; and

locating the 3-D feature within the imaged volume, wherein the 3-D feature comprises a plurality of feature points, and wherein generating the first X-ray image and the second X-ray image comprises, for each feature point:

generating a first image point in an imaging plane by projecting a first X-ray through the feature point in the imaged volume from a first X-ray source, the first image point having a first set of planar coordinates in the imaging plane defined by a first displacement from an imaging axis in a first direction and a second displacement from the imaging axis in a second direction; and

generating a second image point in the imaging plane by projecting a second X-ray through the feature point in the imaged volume from a second X-ray source, the second image point having a second set of planar coordinates in the imaging plane defined by a third displacement from the imaging axis in the first direction and a forth displacement from the imaging axis in the second direction, the first image point and the second image point comprising a conjugate pair of image points corresponding to the feature point.

8. A system, comprising:

a stereoscopic imaging system comprising a first imaging device having a first imaging axis and a second imaging device having a second imaging axis substantially parallel to the first imaging axis, to image a 3-D feature within an imaged volume; and

a processing device coupled with the imaging system, wherein the processing device is configured to locate the 3-D feature within the imaged volume, wherein to image the 3-D feature the imaging system is configured to generate substantially parallel X-ray images of the imaged volume comprising a first X-ray image and a second X-ray image, the first X-ray image including a first image feature corresponding to a 3-D feature within the imaged volume, the second X-ray image including a second image feature corresponding to the 3-D feature within the imaged volume, wherein the second image feature is substantially similar to the first image feature.

9. The system of claim 8 , wherein the processing device is further configured to track the 3-D feature within the imaged volume by registering the 3-D feature with a 3-D pre-treatment volume study of the imaged volume.

10. A system, comprising:

a stereoscopic imaging system comprising a first imaging device having a first imaging axis and a second imaging device having a second imaging axis substantially parallel to the first imaging axis, to image a 3-D feature within an imaged volume; and

a processing device coupled with the imaging system, wherein the processing device is configured to locate the 3-D feature within the imaged volume, wherein to locate the 3-D feature the processing device is configured to match the first image feature with the second image feature to obtain a pair of matched image features and to determine a location of the 3-D feature within the imaged volume from planar coordinates of the pair of matched image features.

11. The system of claim 10 , wherein the first image feature in the first X-ray image comprises a first plurality of image points and the second image feature in the second X-ray image, substantially similar to the first image feature, comprises a second plurality of image points, and wherein to match the image features the processing device is configured to compute a similarity measure between the first image feature and the second image feature and to match the first plurality of image points with the second plurality of image points in a plurality of conjugate pairs of image points.

12. The system of claim 11 , wherein to determine the location of the 3-D feature within the imaged volume, the processing device is configured to map the plurality of conjugate pairs of image points to the plurality of feature points of the 3-D feature in the imaged volume.

13. The system of claim 10 , wherein the 3-D feature in the imaged volume comprises one of a fiducial marker, a curved edge, a corner and an endpoint.

14. The system of claim 10 , wherein the first and second imaging devices are diagnostic imaging devices.

15. The system of claim 14 , wherein the first image feature and the second imaged feature are an anatomical feature within a patient.

16. A system, comprising:

a stereoscopic imaging system comprising a first imaging device having a first imaging axis and a second imaging device having a second imaging axis substantially parallel to the first imaging axis, to image a 3-D feature within an imaged volume; and

a processing device coupled with the imaging system, wherein the processing device is configured to locate the 3-D feature within the imaged volume, wherein the 3-D feature comprises a plurality of feature points, and wherein to generate the substantially parallel X-ray images, the processing device is further configured, for each feature point, to:

generate a first image point in an imaging plane by projecting a first X-ray through the feature point in the imaged volume from a first X-ray source, the first image point having a first pair of planar coordinates in the imaging plane defined by a first displacement from an imaging axis in a first direction and a second displacement from the imaging axis in a second direction; and to

generate a second image point in the imaging plane by projecting a second X-ray through the feature point in the imaged volume from a second X-ray source, the second image point having a second pair of planar coordinates in the imaging plane defined by a third displacement from the imaging axis in the first direction and a forth displacement from the imaging axis in the second direction, the first image point and the second image point comprising a conjugate pair of image points corresponding to the feature point.

17. The system of claim 16 , wherein the first X-ray and the second X-ray subtend an angle at the feature point less than approximately forty-five degrees.

18. An article of manufacture comprising a machine-accessible medium including data that, when accessed by a machine, cause the machine to perform operations, comprising:

imaging a 3-D feature in an imaged volume with two or more in-treatment imaging X-ray sources having substantially parallel imaging axes, wherein imaging the feature comprises:

generating a first X-ray image of the imaged volume comprising a first image feature corresponding to a 3-D feature within the imaged volume; and

generating a second X-ray image substantially parallel to the first X-ray image, comprising a second image feature corresponding to the 3-D feature within the imaged volume, wherein the second image feature is substantially similar to the first image feature; and

locating the 3-D feature within the imaged volume.

19. The article of manufacture of claim 18 , wherein the machine-accessible medium further includes data that cause the machine to perform operations, comprising tracking the 3-D feature within the imaged volume by registering the 3-D feature with a 3-D pre-treatment volume study of the imaged volume.

20. The article of manufacture of claim 18 , wherein locating the feature comprises:

matching the first image feature with the second image feature to obtain a pair of matched image features; and

determining a location of the 3-D feature within the imaged volume from planar coordinates of the pair of matched image features.

21. The article of manufacture of claim 20 , wherein the first image feature in the first X-ray image comprises a first plurality of image points and the second image feature in the second X-ray image, substantially similar to the first image feature, comprises a second plurality of image points, and wherein matching the image features comprises computing a similarity measure between the first image feature and the second image feature and matching the first plurality of image points with the second plurality of image points in a plurality of conjugate pairs of image points.

22. The article of manufacture of claim 21 , wherein determining the location of the 3-D feature within the imaged volume comprises mapping the plurality of conjugate pairs of image points to the plurality of feature points of the 3-D feature within the imaged volume.

23. The article of manufacture of claim 18 , wherein the 3-D feature comprises a plurality of feature points, and wherein generating the first X-ray image and the second X-ray image comprises, for each feature point:

generating a first image point in an imaging plane by projecting a first X-ray through the feature point in the imaged volume from a first X-ray source, the first image point having a first set of planar coordinates in the imaging plane defined by a first displacement from an imaging axis in a first direction and a second displacement from the imaging axis in a second direction; and

generating a second image point in the imaging plane by projecting a second X-ray through the feature point in the imaged volume from a second X-ray source, the second image point having a second set of planar coordinates in the imaging plane defined by a third displacement from the imaging axis in the first direction and a forth displacement from the imaging axis in the second direction, the first image point and the second image point comprising a conjugate pair of image points corresponding to the feature point.

24. The article of manufacture of claim 18 , wherein the 3-D feature within the imaged volume comprise one of a fiducial marker, a curved edge, a corner and an endpoint.

25. An apparatus, comprising:

means for imaging a 3-D feature in an imaged volume with two or more in-treatment imaging X-ray sources having substantially parallel imaging axes, wherein the means for imaging the 3-D feature comprises:

means for generating a first X-ray image of an imaged volume, comprising a first image feature corresponding to a 3-D feature within the imaged volume; and

means for generating a second X-ray image substantially parallel to the first image feature, comprising a second image feature corresponding to the 3-D feature within the imaged volume, wherein the second image feature is substantially similar to the first image feature; and

means for locating the 3-D feature within the imaged volume.

26. The apparatus of claim 25 , further comprising means for tracking the 3-D feature within the imaged volume by registering the 3-D feature with a 3-D pre-treatment volume study of the imaged volume.

27. The apparatus of claim 25 , wherein locating the 3-D feature comprises:

means for matching the first image feature with the second image feature to obtain a pair of matched image features; and

means for determining a location of the 3-D feature within the imaged volume from planar coordinates of the pair of matched image features.

28. The apparatus of claim 25 , further comprising means for registering the location of the 3-D feature with a 3-D scan of the imaged volume.

Assignments (11)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 13, 2025
From: ACCURAY INCORPORATED
To: ACCURAY LLC
Reel/Frame 072421/0584 →
RELEASE OF SECURITY INTEREST Recorded Jun 6, 2025
From: FIRST-CITIZENS BANK & TRUST COMPANY
To: ACCURAY INCORPORATED
Reel/Frame 071638/0034 →
RELEASE OF SECURITY INTEREST Recorded May 20, 2021
From: MIDCAP FUNDING IV TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING X TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING IV TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST)
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 056318/0559 →
RELEASE OF SECURITY INTEREST Recorded May 20, 2021
From: MIDCAP FINANCIAL TRUST
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 056318/0751 →
SECURITY INTEREST Recorded May 14, 2021
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: SILICON VALLEY BANK, AS ADMINISTRATIVE AND COLLATERAL AGENT
Reel/Frame 056247/0001 →
ASSIGNMENT OF SECURITY AGREEMENTS Recorded Mar 1, 2019
From: MIDCAP FUNDING X TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FUNDING IV TRUST, AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST), AS EXISTING ADMINISTRATIVE AGENT
To: MIDCAP FUNDING IV TRUST, AS SUCCESSOR TO EXISTING ADMINISTRATIVE AGENT
Reel/Frame 048481/0804 →
SECURITY INTEREST Recorded Dec 19, 2017
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: MIDCAP FINANCIAL TRUST
Reel/Frame 044910/0685 →
RELEASE OF SECURITY INTEREST Recorded Jun 15, 2017
From: CERBERUS BUSINESS FINANCE, LLC. AS COLLATERAL AGENT
To: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
Reel/Frame 042821/0580 →
SECURITY INTEREST Recorded Jun 15, 2017
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: MIDCAP FUNDING IV TRUST (AS SUCCESSOR BY ASSIGNMENT FROM MIDCAP FINANCIAL TRUST)
Reel/Frame 042826/0358 →
ASSIGNMENT FOR SECURITY - PATENTS Recorded Jan 13, 2016
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: CERBERUS BUSINESS FINANCE, LLC, AS COLLATERAL AGENT
Reel/Frame 037513/0170 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 7, 2006
From: BODDULURI, MOHAN
To: ACCURAY INCORPORATED
Reel/Frame 018492/0251 →
Continuity (1)
Related Publication 20080002809A1 · Jan 3, 2008