Device and process for producing fiber products and fiber products produced thereby
View Patent ↗The present invention is directed to a fiber, preferably bone fiber, having a textured surface, which acts as an effective binding substrate for bone-forming cells and for the induction or promotion of new bone growth by bone-forming cells, which bind to the fiber. Methods of using the bone fibers to induce or promote new bone growth and bone material compositions comprising the bone fibers are also described. The invention further relates to a substrate cutter device and cutter, which are effective in producing substrate fibers, such as bone fibers.
1. A substrate cutting device comprising,
a cutter comprising a blade section, wherein the blade section includes at least one row of teeth and wherein each tooth includes a primary cutting angle and a secondary cutting angle;
a clamping mechanism for holding a substrate having a lengthwise grain;
a slide mechanism that is coupled to the cutter; wherein the clamping mechanism is disposed relative to the slide mechanism so that the slide mechanism slides substantially parallel to a lengthwise grain of a clamped substrate and the blade section contacts the substrate during operation of the cutting device;
a pneumatically operated first actuation unit that moves the slide mechanism during operation of the cutting device;
a pneumatically operated second actuation unit that positions the clamping mechanism;
at least one fiber channel; and
a controller, where the controller controls the first actuation unit and the second actuation unit.
2. The substrate cutting device of claim 1 , further comprising a sensor for detecting the prescribed conditions during operation of the cutting device.
3. The substrate cutting device of claim 1 , wherein the controller varies a speed at which the slide mechanism slides during operation of the cutting device.
4. The substrate cutting device of claim 1 , wherein the controller varies a force at which the blade section contacts the bone tissue during operation of the cutting device.
5. The substrate cutting device of claim 1 , wherein the second actuation unit applies a force of 150 lbs-250 lbs to the clamping mechanism during operation of the cutting device.
6. The substrate cutting device of claim 1 , wherein the second actuation unit applies a force of 200 lbs to the clamping mechanism during operation of the cutting device.
7. The substrate cutting device of claim 1 , wherein each tooth includes at least one predetermined cutting angle.
8. The substrate cutting device of claim 1 , wherein said primary cutting angle is between about 3° and about 6°.
9. The substrate cutting device of claim 1 , wherein said primary cutting angle is about 4°.
10. The substrate cutting device of claim 1 , wherein said secondary cutting angle is between about 10° and about 18°.
11. The substrate cutting device of claim 1 , wherein said secondary cuffing angle is between about 12° and about 16°.
12. The substrate cutting device of claim 1 , wherein said secondary cutting angle is about 14°.
13. A method of producing substrate fibers comprising placing a substrate into the substrate cutting device of claim 1 and cutting substrate fibers from the substrate.
14. The method of claim 13 , wherein the substrate is bone, bone tissue, or soft tissue.
15. The method of claim 14 , wherein the substrate is plasticized.
16. The method of claim 14 , wherein the substrate is freeze dried.
17. The method of claim 14 , wherein the substrate is frozen.
18. The method of claim 14 , wherein the method further comprises combining the substrate with glycerol prior to cutting.
19. The method of claim 14 , wherein the bone is newly formed bone or implant bone.
20. The method of claim 14 , wherein the substrate is derived from a mammalian source.
21. The method of claim 20 , wherein the substrate is derived from a human.
22. The method of claim 21 , wherein the substrate is bone tissue.
23. The method of claim 22 , wherein the bone tissue is plasticized.
24. The method of claim 22 , wherein the method further comprises combining the bone tissue with glycerol prior to cutting.