IP Library Granted Patent US 7,769,216
Granted Patent B2
US 7,769,216 · App. 11/323,939 · Granted Aug 3, 2010

Facilitating comparison of medical images

Assignee: Hologic, Inc.
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Quick Facts
Patent No.
US 7,769,216
App. No.
11/323,939
Filed
Dec 29, 2005
Granted
Aug 3, 2010
Kind
B2
Art Unit
2624
USPC
382/128
Abstract

Facilitating viewer comparison of a plurality of medical images of at least one body part on a softcopy review workstation is described. First and second medical images are displayed such that the second medical image appears as a spatially registered underlay to the first medical image exposed through an aperture therein. The aperture comprises at least one edge that is viewer-manipulable in a back-and-forth manner so that the first and second medical images can be visually compared with minimal eye movement. For a temporal comparison embodiment, the first and second medical images comprise identical views of the same body part acquired at different times. For a cross-modality comparison embodiment, the first and second medical images are acquired substantially concurrently, or at different times, using different medical imaging modalities. For a bilateral comparison embodiment, the first and second images are corresponding views of two laterally corresponding body parts.

Claims (30)

1. A method for facilitating viewer comparison of a plurality of medical images of at least one body part on a softcopy review workstation, the softcopy review workstation including at least one processor and a display device, the method being implemented by the softcopy review workstation, the method comprising:

receiving, by the softcopy review workstation, first and second medical images of the at least one body part; and

displaying, by the softcopy review workstation, said first and second medical images on said display device such that the second medical image appears as a spatially registered underlay to the first medical image exposed through a first aperture therein, the first medical image masking the second medical image outside the first aperture, the second medical image masking the first medical image inside the first aperture, said first aperture having at least one edge that is viewer-manipulable in a back-and-forth manner so that the first and second medical images can be visually compared with minimal eye movement.

2. The method of claim 1 , wherein said first aperture comprises one of (i) an entire half-plane of the first medical image such that said at least one edge consists of a single line thereacross, and (ii) a viewer-definable geometric shape including said at least one edge that openably and closeably exposes the second medical image from underneath the first medical image according to viewer manipulations of said at least one edge.

3. The method of claim 1 , wherein said first and second medical images comprise (i) identical views of a same body part acquired at different times using a same medical imaging modality, or (ii) corresponding views of laterally corresponding body parts acquired using the same medical imaging modality, wherein said medical imaging modality is selected from the group consisting of: x-ray, ultrasound, computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT).

4. The method of claim 1 , wherein said first and second medical images are acquired substantially concurrently using different medical imaging modalities selected from the group consisting of: x-ray, ultrasound, computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT).

5. The method of claim 1 , wherein said first and second medical images are derived from nearby parallel planes of a common data volume acquired using a three-dimensional imaging modality.

6. The method of claim 1 , wherein said first and second medical images represent nearby parallel planes of a breast volume acquired from an x-ray tomosynthesis modality.

7. The method of claim 1 , wherein said at least one edge is sufficiently sharp such that a lateral boundary between the first and second medical images corresponding to said at least one edge is visually apparent even when differences between the first and second medical images are relatively slight in a vicinity of said at least one edge.

8. The method of claim 7 , further comprising processing said first and second medical images near said at least one edge to provide visual emphasis of said lateral boundary.

9. The method of claim 8 , wherein said processing comprises one of more of high-pass spatial filtering, grayscale ramping, colorization, and image warping.

10. A softcopy review workstation, comprising:

a display device;

a user input device; and

a processor in communication with said display device and said user input device, said processor causing said display device to display a first medical image and a second medical image of at least one body part such that the second medical image appears as a spatially registered underlay to the first medical image exposed through a first aperture therein, the first medical image masking the second medical image outside the first aperture, the second medical image masking the first medical image inside the first aperture, said first aperture having at least one edge that is movable by actuation of said user input device, whereby the first and second medical images can be visually compared with minimal user eye movement.

11. The softcopy review workstation of claim 10 , wherein said first aperture comprises one of (i) an entire half-plane of the first medical image such that said at least one edge consists of a single line thereacross, and (ii) a user-definable geometric shape including said at least one edge that openably and closeably exposes the second medical image from underneath the first medical image according to said actuation of said user input device.

12. The softcopy review workstation of claim 10 , wherein said first and second medical images comprise (i) identical views of a same body part acquired at different times using a same medical imaging modality, or (ii) corresponding views of laterally corresponding body parts acquired using the same medical imaging modality, wherein said medical imaging modality is selected from the group consisting of: x-ray, ultrasound, computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT).

13. The softcopy review workstation of claim 10 , wherein said first and second medical images are acquired substantially concurrently using different medical imaging modalities selected from the group consisting of: x-ray, ultrasound, computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT).

14. The softcopy review workstation of claim 10 , wherein said first and second medical images are derived from nearby parallel planes of a common data volume acquired using a three-dimensional imaging modality.

15. The softcopy review workstation of claim 10 , wherein said first and second medical images represent nearby parallel planes of a breast volume acquired from an x-ray tomosynthesis modality.

16. The softcopy review workstation of claim 10 , wherein said at least one edge is sufficiently sharp such that a lateral boundary between the first and second medical images corresponding to said at least one edge is visually apparent even when differences between the first and second medical images are relatively slight in a vicinity of said at least one edge.

17. A computer readable medium tangibly embodying one or more sequences of instructions wherein execution of the one or more sequences of instructions by one or more processors causes the one or more processors to facilitate viewer comparison of a plurality of medical images of at least one body part, comprising:

displaying said first and second medical images of said at least one body part such that the second medical image appears as a spatially registered underlay to the first medical image exposed through a first aperture therein, the first medical image masking the second medical image outside the first aperture, the second medical image masking the first medical image inside the first aperture; and

slidably translating at least one edge of said first aperture responsive to at least one viewer input so that the first and second medical images can be visually compared with minimal eye movement.

18. The computer readable medium of claim 17 , wherein said first aperture comprises one of (i) an entire half-plane of the first medical image such that said at least one edge consists of a single line thereacross, and (ii) a viewer-definable geometric shape including said at least one edge that openably and closeably exposes the second medical image from underneath the first medical image according to said slidable translation of said at least one edge.

19. The computer readable medium of claim 17 , wherein said first and second medical images comprise (i) identical views of a same body part acquired at different times using a same medical imaging modality, or (ii) corresponding views of laterally corresponding body parts acquired using the same medical imaging modality, wherein said medical imaging modality is selected from the group consisting of: x-ray, ultrasound, computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT).

20. The computer readable medium of claim 17 , wherein said first and second medical images are acquired substantially concurrently using different medical imaging modalities selected from the group consisting of: x-ray, ultrasound, computerized tomography (CT), magnetic resonance imaging (MRI), positron emission tomography (PET), and single-photon emission computed tomography (SPECT).

21. The computer readable medium of claim 17 , wherein said first and second medical images represent nearby parallel planes of a breast volume acquired from an x-ray tomosynthesis modality.

22. The computer readable medium of claim 17 , wherein said first and second medical images are derived from nearby parallel planes of a common data volume acquired using a three-dimensional imaging modality.

23. The computer readable medium of claim 17 , wherein said at least one edge is sufficiently sharp such that a lateral boundary between the first and second medical images corresponding to said at least one edge is visually apparent even when differences between the first and second medical images are relatively slight in a vicinity of said at least one edge.

Assignments (13)
RELEASE OF SECURITY INTEREST Recorded Apr 28, 2026
From: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
To: HOLOGIC, INC., ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO DIRECT RADIOGRAPHY CORP.; CYTYC CORPORATION, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO BIOLUCENT, LLC; CYTYC SURGICAL PRODUCTS, LLC, AS SUCCESSOR-BY-CONVERSION TO CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; GEN-PROBE INCORPORATED, ON ITS OWN BEHALF AND AS SUCCESSOR-BY-MERGER TO THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.
Reel/Frame 075566/0039 →
SECURITY INTEREST Recorded Apr 8, 2026
From: BIOTHERANOSTICS, INC.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; CYTYC CORPORATION; SUROS SURGICAL SYSTEMS, INC.; GYNESONICS, INC.; BOLDER SURGICAL, LLC; FAXITRON BIOPTICS, LLC; HEALTH BEACONS, INC.; HOLOGIC, INC.
To: ROYAL BANK OF CANADA, AS COLLATERAL AGENT
Reel/Frame 075462/0440 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 035820 FRAME: 0239. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY INTEREST RELEASE. Recorded Nov 9, 2017
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 044727/0529 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT PATENT NO. 8081301 PREVIOUSLY RECORDED AT REEL: 028810 FRAME: 0745. ASSIGNOR(S) HEREBY CONFIRMS THE SECURITY AGREEMENT. Recorded Nov 9, 2017
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 044432/0565 →
SECURITY AGREEMENT Recorded Aug 7, 2015
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; DIRECT RADIOGRAPHY CORP.; GEN-PROBE INCORPORATED; GEN-PROBE PRODESSE, INC.; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.
To: BANK OF AMERICA, N.A., AS COLLATERAL AGENT
Reel/Frame 036307/0199 →
SECURITY INTEREST RELEASE REEL/FRAME 028810/0745 Recorded Jun 4, 2015
From: GOLDMAN SACHS BANK USA, AS COLLATERAL AGENT
To: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
Reel/Frame 035820/0239 →
SECURITY AGREEMENT Recorded Aug 1, 2012
From: HOLOGIC, INC.; BIOLUCENT, LLC; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS, LIMITED PARTNERSHIP; SUROS SURGICAL SYSTEMS, INC.; THIRD WAVE TECHNOLOGIES, INC.; GEN-PROBE INCORPORATED
To: GOLDMAN SACHS BANK USA
Reel/Frame 028810/0745 →
TERMINATION OF PATENT SECURITY AGREEMENTS AND RELEASE OF SECURITY INTERESTS Recorded Aug 26, 2010
From: GOLDMAN SACHS CREDIT PARTNERS, L.P., AS COLLATERAL AGENT
To: HOLOGIC, INC.; R2 TECHNOLOGY, INC.; SUROS SURGICAL SYSTEMS, INC.; BIOLUCENT, LLC; DIRECT RADIOGRAPHY CORP.; CYTYC SURGICAL PRODUCTS II LIMITED PARTNERSHIP; CYTYC SURGICAL PRODUCTS LIMITED PARTNERSHIP; CYTYC CORPORATION; CYTYC SURGICAL PRODUCTS III, INC.; CYTYC PRENATAL PRODUCTS CORP.; THIRD WAVE TECHNOLOGIES, INC.
Reel/Frame 024892/0001 →
21ST SUPPLEMENT TO PATENT SECURITY AGREEMENT Recorded Mar 29, 2010
From: HOLOGIC, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
Reel/Frame 024151/0435 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 8, 2009
From: R2 TECHNOLOGY, INC.
To: HOLOGIC, INC.
Reel/Frame 023620/0362 →
PATENT SECURITY AGREEMENT Recorded Jul 29, 2008
From: R2 TECHNOLOGY, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P., AS COLLATERAL AGENT
Reel/Frame 021301/0838 →
PATENT SECURITY AGREEMENT Recorded Oct 26, 2007
From: R2 TECHNOLOGY, INC.
To: GOLDMAN SACHS CREDIT PARTNERS L.P.
Reel/Frame 020024/0231 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 29, 2005
From: DOI, TAKESHI; SIMCIC, VILIM; ROEHRIG, JIMMY R.
To: R2 TECHNOLOGY, INC.
Reel/Frame 017441/0425 →
Continuity (1)
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