Catheter with multiple ultrasound radiating members
View Patent ↗A catheter for delivering ultrasonic energy and therapeutic compounds to a treatment site within a patient's vasculature comprises a tubular body. The tubular body has a proximal region and a distal region opposite the proximal region. The catheter further comprises a plurality of fluid delivery lumens formed into the tubular body. The catheter further comprises an inner core configured for insertion into the tubular body. The inner core comprises an elongate electrical conductor having a plurality of flattened regions, each flattened region having a first flat side and a second flat side opposite the first flat side. The inner core further comprises a plurality of ultrasound radiating members mounted in pairs to the flattened regions of the elongate electrical conductor. A first ultrasound radiating member is mounted to the first flat side of the elongate electrical conductor, and a second ultrasound radiating member is mounted to the second flat side of the elongate electrical conductor. The catheter further comprises control electronics configured to apply a driving signal to at least two, but fewer than all, of the ultrasound radiating members.
1. A catheter system for delivering ultrasonic energy to a treatment site, the catheter system comprising:
a tubular body having a proximal end, a distal end and a treatment zone located between the distal end and the proximal end; and
an ultrasonic assembly positioned within the treatment zone; the ultrasonic assembly comprising a common electrical conductor and a plurality of ultrasonic transducer pairs along the common electrical conductor, each ultrasonic transducer pair comprising a first ultrasound transducer having a first portion, a second ultrasound transducer having a second portion;
wherein the first portion of the first transducer and the second portion of the second transducer face each other and are electrically coupled to the common electrical conductor.
2. The catheter system of claim 1 , wherein the first portion of the first transducer and the second portion of the second transducer are mounted to the common electrical conductor.
3. The catheter system of claim 1 , wherein the first portion of the first transducer and the second portion of the second transducer are substantially flat.
4. The catheter system of claim 3 , wherein the common electrical conductor includes a first flat portion and a second flat portion, the first portion of the first transducer being mounted to the first flat portion and the second portion of the second transducer being mounted to the second flat portion.
5. The catheter system of claim 1 , further comprising a therapeutic compound delivery lumen that extends through the tubular body and terminates at least one outlet positioned in the treatment zone.
6. The catheter system of claim 1 , wherein the ultrasonic assembly is positioned within an inner core.
7. The catheter system of claim 6 , wherein the inner core can be removably inserted into the tubular body so as to position the ultrasonic assembly in the treatment zone.
8. The catheter system of claim 1 , wherein the first transducer is electrically coupled to a first wire and the second transducer is electrically coupled to a second wire.
9. The catheter system of claim 8 , further comprising a control system configured such that a voltage can be applied simultaneously across the first and second transducers so as to drive the first and second transducers.
10. The catheter system of claim 1 , wherein the treatment zone has a greater acoustic transparency than a proximal region of the tubular body.
11. The catheter system of claim 1 , wherein a distance between a most proximal ultrasound transducer pair and a most distal ultrasound transducer pair is in the range of approximately 5 to 70 cm.
12. The catheter system of claim 1 , wherein the catheter system includes 5 to 50 cm of ultrasound transducer pairs.
13. The catheter system of claim 1 , wherein the plurality of ultrasound transducer pairs are grouped into a plurality of electrical groups, each group of ultrasound transducer pairs being independently drivable by a control system.
14. The catheter system of claim 13 , wherein each member of an electrical group is spatially grouped together.
15. The catheter system of claim 13 , wherein each member of an electrical group is positioned adjacent to at least one other member of the electrical group.
16. A catheter system for delivering ultrasonic energy to a treatment site, the catheter comprising:
a tubular body having a proximal end, a distal end and a treatment zone located between the distal and proximal ends; and
an ultrasonic assembly positioned within the treatment zone; the ultrasonic assembly comprising a common electrical conductor and a plurality of ultrasonic transducer pairs, each ultrasonic transducer pair comprising a rectangular solid first ultrasonic element and a rectangular solid second ultrasonic element;
wherein the first and second ultrasonic elements are mounted on opposite sides of the common electrical conductor.
17. The catheter system of claim 16 , wherein the common electrical conductor includes a first flat portion and a second flat portion, a first side of the first transducer being mounted to the first flat portion and a second side of the second transducer being mounted to the second flat portion.
18. The catheter system of claim 16 , further comprising a therapeutic compound delivery lumen that extends through the tubular body and terminates at one or more therapeutic compound delivery outlets positioned in the treatment zone.
19. The catheter system of claim 16 , wherein the ultrasonic assembly is positioned within an inner core.
20. The catheter system of claim 19 , wherein the inner core can be removably inserted into the tubular body so as to position the ultrasonic assembly in the treatment zone.
21. The catheter system of claim 16 , wherein the first transducer is electrically coupled to a first wire and the second transducer is electrically coupled to a second wire.
22. The catheter system of claim 21 , further comprising a control system configured such that a voltage can be applied simultaneously across the first and second transducers.
23. The catheter system of claim 16 , wherein the treatment zone has a greater acoustic transparency than a proximal region of the tubular body.
24. The catheter system of claim 16 , wherein a distance between a most proximal ultrasound transducer pair and a most distal ultrasound transducer pair is in the range of approximately 5 to 70 cm.
25. The catheter system of claim 16 , wherein the catheter system includes 5 to 50 cm of ultrasound transducer pairs.