IP Library Granted Patent US 7,977,310
Granted Patent B2
US 7,977,310 · App. 12/140,598 · Granted Jul 12, 2011

Method for reducing cardiovascular morbidity and mortality in prediabetic patients and patients with type 2 diabetes

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Quick Facts
Patent No.
US 7,977,310
App. No.
12/140,598
Granted
Jul 12, 2011
Kind
B2
Abstract

This invention relates to a method of reducing cardiovascular morbidity and mortality in a prediabetic or Type 2 Diabetes patient population. The method comprises administering an effective dosage of a long acting insulin, preferably insulin glargine, to a prediabetic or Type 2 Diabetes patient.

Claims (10)

1. A method of preventing an increase in left ventricular mass in a patient diagnosed with a disease or condition selected from the group of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), comprising administering to said patient a therapeutically effective dosage of a long acting insulin.

2. The method according to claim 1 wherein the long acting insulin is insulin glargine.

3. The method according to claim 2 wherein the effective dosage is in the range of about 2 to about 150 IU per day.

4. The method according to claim 3 wherein the effective dosage is in the range of about 2 to about 80 IU per day.

5. The method according to claim 4 wherein the effective dosage is in the range of about 2 to about 40 IU per day.

6. A method of preventing an increase in carotid intimal thickness in a patient diagnosed with a disease or condition selected from the group of impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), comprising administering to said patient a therapeutically effective dosage of a long acting insulin.

7. The method according to claim 6 wherein the long acting insulin is insulin glargine.

8. The method according to claim 7 wherein the effective dosage is in the range of about 2 to about 150 IU per day.

9. The method according to claim 8 wherein the effective dosage is in the range of about 2 to about 80 IU per day.

10. The method according to claim 9 wherein the effective dosage is in the range of about 2 to about 40 IU per day.

Assignments (2)
MERGER Recorded Jan 19, 2015
From: AVENTIS PHARMACEUTICALS INC.
To: AVENTISUB LLC
Reel/Frame 034781/0334 →
CERTIFICATE OF CONVERSION Recorded Dec 9, 2014
From: AVENTISUB INC.
To: AVENTISUB LLC
Reel/Frame 034566/0976 →