Network and methods for integrating individualized clinical test results and nutritional treatment
The present invention provides networks and method for linking consumers and nutritional pharmacogeneticists offering personalized nutritional information through a central network site. The network includes a central integration site through which network members communicate with each other. The central integration site stores two or more databases in the storage medium. The databases store biochemical marker data information, nutritional and/or drug data information including a record for association and effect of nutrients with a particular biochemical marker, and/or drug. The network of the invention provides individualized nutritional diagnostic and treatment to consumers on the basis of their genetic test results.
1. An interactive computerized method of linking a consumer and a nutritional pharmacologist offering personalized nutritional information to the consumer comprising;
providing a central integration site comprising a computer through which the nutritional pharmacologist and the consumer communicate with each other;
storing a non-transitory computer readable medium on said computer including a first database storing biochemical marker data obtained through statistical analysis of plurality of biochemical markers obtained from testing a human test group, wherein said computer determines a low, a high and a target value and a normal range of values for each said plurality of biochemical markers of said human test group; and a second database storing a nutritional record for plurality of nutrients and information on an effect of each of said plurality of nutrients has on said each of said plurality of biochemical markers obtained from said human test group;
receiving a consumer's genetic test containing a numerical value for said at least one biochemical marker, wherein said at least one biochemical marker comprises, Angiotensin I-Converting Enzyme, S-adenosylhomocysteine hydrolase, Apolipoprotein C, Cystathionine beta-synthase, Cholesteryl ester transfer protein, Catechol O methyl transferase, Glutathione S-transferase, Interleukin 6, Lipoprotein lipase, Monoamine oxidase A, Methylene Tetrahydrofolate reductase, Methionine synthase, Methionine synthase, Methionine synthase reductase, N-acetyl transferase, Nitric Oxide synthase, Peroxisomal Proliferator Activated Receptor, Superoxide Dismutase, Sulfite oxidase, Tumor Necrosis Factor-alpha, Vitamin D Receptor, or a combination thereof,
generating a consumer's biochemical marker level set by comparing said numerical value of said at least one biochemical marker indicated in the consumer's genetic test against said target value of the biochemical marker data of said first database to determine; whether the consumer's numerical value is higher than, equal to, or lower than the target value, and whether the consumer's numerical value is within the normal range of values determined for said human test group;
comparing said biochemical marker level set with said nutritional record stored in the second database to determine one or more nutrients that demonstrate a supportive effect on said at least one biochemical marker by regulating a value of said at least one biochemical marker towards said target value;
generating a status report indicating a personalized nutritional information for the consumer through said central integration site; wherein the status report shows nutrients that are indicated and/or contraindicated based on results of the comparing step;
communicating said status report to the consumer through said central integration site, and
periodically updating said nutritional pharmacologist with new clinical and scientific reports regarding metabolic pharmacology of said at least one biochemical marker, wherein the method determines biochemical imbalances specific to the consumer and provides personalized treatment choices to the consumer.
2. The interactive computerized method of claim 1 , wherein the biochemical marker is an expressed gene product.
3. The interactive computerized method of claim 1 , wherein said at least one nutrient comprises vitamins, minerals, small molecules, lipids, proteins, carbohydrates, electrolytes, enzymes, or coenzymes, or a combination thereof.
4. The interactive computerized method of claim 1 utilizing the Internet.
5. The interactive computerized method of claim 1 utilizing an intranet.
6. The interactive computerized method of claim 1 , wherein the consumer's genetic test is received through systems comprising an interactive telephone system, an automatic speech recognition system, one or more questionnaire forms submitted via facsimile, one or more questionnaire forms manually entered or scanned into the computer system, a computer keyboard, a telephone keyboard, a pointing device, or any combination thereof.
7. The interactive computerized method of claim 1 , wherein said central integration site communicates said status report to said consumer via a printer, e-mail, a facsimile device, a visual display, a speech playback system, telephone, or a combination thereof.
8. The interactive computerized method of claim 1 , wherein the genetic test results indicate mutation, substitution, replacement, repetition, deletion, or translocation of one or more genes.
9. The interactive computerized method of claim 1 , wherein said non-transitory computer readable medium further comprises a third database that maintains drug records for determining interaction between drugs and said at least one biochemical marker.