IP Library Granted Patent US 8,017,633
Granted Patent B2
US 8,017,633 · App. 11/885,450 · Granted Sep 13, 2011

Roflumilast for the treatment of diabetes mellitus

Assignee: Nycomed GmbH
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Quick Facts
Patent No.
US 8,017,633
App. No.
11/885,450
Granted
Sep 13, 2011
Kind
B2
Abstract

The invention relates to the use of Roflumilast and/or Roflumilast N-Oxide for the treatment of diabetes mellitus and accompanying disorders thereof. The invention additionally relates to combinations of Roflumilast and/or Roflumilast N-Oxide with other active agents for the treatment of diabetes mellitus.

Claims (4)

1. A pharmaceutical composition comprising a pharmaceutical formulation including an amount of a compound of formula 1.1

or a pharmaceutically acceptable salt thereof and/or a compound of formula 1.2

or a pharmaceutically acceptable salt thereof, an amount of a dipeptidyl-peptidase IV inhibitor selected from the group consisting of SITAGLIPTIN, SAXAGLIPTIN, VILDAGLIPTIN, DENAGLIPTIN, P32/98, NVP-DPP-728 and the pharmaceutically acceptable salts of these compounds, wherein the first amount and the second amount together comprise an effective amount for the treatment of diabetes mellitus type 2 , and at least one pharmaceutically acceptable auxiliary.

2. The pharmaceutical composition according to claim 1 , wherein the dipeptidyl-peptidase IV inhibitor is selected from the group consisting of SITAGLIPTIN and the pharmaceutically acceptable salts thereof.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 11, 2017
From: TAKEDA GMBH
To: ASTRAZENECA AB
Reel/Frame 041328/0362 →
CHANGE OF NAME Recorded Jul 29, 2015
From: NYCOMED GERMANY HOLDING GMBH
To: TAKEDA GMBH
Reel/Frame 036205/0192 →
MERGER Recorded Jul 28, 2015
From: TAKEDA GMBH
To: NYCOMED ASSET MANAGEMENT GMBH
Reel/Frame 036193/0178 →
MERGER Recorded Jul 28, 2015
From: NYCOMED ASSET MANAGEMENT GMBH
To: NYCOMED GERMANY HOLDING GMBH
Reel/Frame 036201/0261 →
CHANGE OF NAME Recorded Mar 21, 2013
From: NYCOMED GMBH
To: TAKEDA GMBH
Reel/Frame 030062/0599 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 31, 2007
From: KLEY, HANS-PETER; HANAUER, GUIDO; HAUSER, DANIELA; SCHMIDT, BEATE; BREDENBROEKER, DIRK; WURST, WILHELM; KEMKOWSKI, JOERG
To: NYCOMED GMBH
Reel/Frame 019827/0427 →
Priority Claims (1)
EP 05101772 · Mar 8, 2005 · regional
Continuity (1)
Related Publication 20080214625A1 · Sep 4, 2008