IP Library Granted Patent US 8,288,384
Granted Patent B2
US 8,288,384 · App. 12/619,577 · Granted Oct 16, 2012

Heterocyclic receptor agonists for the treatment of diabetes and metabolic disorders

Assignee: Metabolex, Inc.
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Quick Facts
Patent No.
US 8,288,384
App. No.
12/619,577
Granted
Oct 16, 2012
Kind
B2
Abstract

Compounds and methods are provided for the treatment of, inter alia, Type II diabetes and other diseases associated with poor glycemic control. The compounds of the invention are orally active.

Claims (1)

1. A method of treating Type II diabetes, said method comprising administering to a subject in need of such treatment an effective amount of a compound that is that is 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine or a pharmaceutically acceptable salt thereof.

Assignments (4)
RELEASE OF SECURITY INTEREST Recorded Aug 7, 2015
From: SILICON VALLEY BANK; OXFORD FINANCE LLC
To: CYMABAY THERAPEUTICS, INC.
Reel/Frame 036307/0406 →
SECURITY AGREEMENT Recorded Nov 22, 2013
From: CYMABAY THERAPEUTICS, INC.
To: SILICON VALLEY BANK; OXFORD FINANCE LLC
Reel/Frame 031710/0508 →
CHANGE OF NAME Recorded Nov 6, 2013
From: METABOLEX, INC.
To: CYMABAY THERAPEUTICS, INC.
Reel/Frame 031589/0193 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 12, 2010
From: CHEN, XIN; CHENG, PENG; CLEMENS, L EDWARD; JOHNSON, JEFFREY D; MA, JINGYUAN; MURPHY, ALISON; NASHASHIBI, IMAD; RABBAT, CHRISTOPER J; SONG, JIANGAO; WILSON, MARIA E; ZHU, YAN; ZHAO, ZUCHUN
To: METABOLEX INC.
Reel/Frame 023770/0649 →
Continuity (3)
Division 11964461 · Dec 26, 2007
Provisional Application 60877903 · Dec 28, 2006
Related Publication 20100130511A1 · May 27, 2010