Fixation devices for variation in engagement of tissue
Devices, systems and methods are provided for tissue approximation and repair at treatment sites, particularly in those procedures requiring minimally-invasive or endovascular access to remote tissue locations. Fixation devices are provided to fix tissue in approximation with the use of distal elements. In some embodiments, the fixation devices have at least two distal elements and an actuatable feature wherein actuation of the feature varies a dimension of the at least two distal elements. In other embodiments, the fixation devices have at least two pairs of distal elements wherein the pairs of distal elements are moveable to engage tissue between opposed pairs of distal elements. Systems are also provided having fixation devices and accessories.
1. A fixation device for engaging tissue, said device comprising:
at least two distal elements each having a first end, a free end opposite the first end, an engagement surface therebetween for engaging the tissue, and a longitudinal axis extending between the first end and the free end, the first ends of the two or more distal elements being movably coupled together such that the at least two distal elements are movable to engage tissue with the engagement surfaces, wherein the engagement surface comprises a concave shape for receiving the tissue; and
an actuatable feature coupled to at least one of the at least two distal elements, wherein actuation of the feature varies a dimension of the at least one of the at least two distal elements which varies the size of its engagement surface.
2. The device of claim 1 , further comprising two or more proximal elements, wherein each of the two or more proximal elements are at least partially recessed in the corresponding concave engagement surface of a distal element.
3. The device of claim 1 , wherein each of the at least two distal elements has a width transverse to its longitudinal axis, and wherein the actuatable feature is configured so that actuation varies its width.
4. The device of claim 3 , wherein the actuatable feature comprises at least one loop which is extendable laterally outwardly in a direction transverse to the longitudinal axis.
5. The device of claim 3 , wherein the actuatable feature comprises at least one flap which is extendable laterally outwardly in a direction transverse to the longitudinal axis.
6. The device of claim 3 , wherein the actuatable feature comprises at least one pontoon which is expandable laterally outwardly in a direction transverse to the longitudinal axis.
7. The device of claim 6 , wherein the pontoon is expanded by inflation.
8. The device of claim 1 , wherein each of the at least two distal elements has a length along its longitudinal axis, and wherein the actuatable feature is configured so that actuation varies its length.
9. The device of claim 8 , wherein the actuatable feature comprises at least one loop which is extendable outwardly from its free end along its longitudinal axis.
10. The device of claim 8 , wherein each of the at least two distal elements comprises an elongate arm, and wherein the actuatable feature comprises an extension arm coupled with the elongate arm.
11. The device of claim 10 , wherein the extension arm is coupled with the elongate arm by a cam such that rotation of the cam advances the extension arm along the longitudinal axis.
12. The device of claim 10 , wherein each distal element is moveable from a closed position wherein the engagement surfaces of the at least two distal elements are closer together to an open position wherein the engagement surfaces of the at least two distal elements are further apart, and wherein movement between the closed and open position advances the extension arm of each distal element along its longitudinal axis.
13. The device of claim 1 , wherein each of the at least two distal elements has a width transverse to its longitudinal axis and a length along its longitudinal axis, and wherein the actuatable feature is configured so that actuation varies its width and length.
14. The device of claim 1 , wherein the at least two distal elements are in an opposed orientation so that the engagement surfaces face one another such that the tissue is captured therebetween.
15. The device of claim 1 , wherein the at least two distal elements are alignable so that the corresponding longitudinal axes are substantially parallel with one another.