Granted Patent
B2
US 8,338,439 · App. 12/648,693 · Granted Dec 25, 2012
2,4-disubstituted pyrimidines useful as kinase inhibitors
Assignee:
Celgene Avilomics Research, Inc.
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Abstract
The present invention provides 2,4-disubstituted pyrimidine compounds useful as kinase inhibitors, pharmaceutically acceptable compositions thereof, and methods of using the same. In some embodiments, the present invention provides a compound of formula I-a or I-b: wherein each of Ring A, Ring B, W 1 , W 2 , R y , R v , R x , m, p, and R 1 is described herein.
Claims (3)
1. A compound selected from the group consisting of:
or a pharmaceutically acceptable salt thereof.
2. A pharmaceutical composition comprising a compound according to claim 1 , and a pharmaceutically acceptable adjuvant, carrier, or vehicle.
Assignments (4)
NUNC PRO TUNC ASSIGNMENT
Recorded May 3, 2023
From: CELGENE CAR LLC
To: BRISTOL-MYERS SQUIBB COMPANY
Reel/Frame 063526/0959 →
MERGER AND CHANGE OF NAME
Recorded Feb 16, 2017
From: CELGENE AVILOMICS RESEARCH, INC.; CELGENE CAR LLC
To: CELGENE CAR LLC
Reel/Frame 041738/0041 →
CHANGE OF NAME
Recorded Sep 28, 2012
From: AVILA THERAPEUTICS, INC.
To: CELGENE AVILOMICS RESEARCH, INC.
Reel/Frame 029058/0066 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 26, 2010
From: SINGH, JUSWINDER; PETTER, RUSSELL; TESTER, RICHLAND WAYNE; KLUGE, ARTHUR F.; MAZDIYASNI, HORMOZ; WESTLIN, WILLIAM FREDERICK, III; NIU, DEQIANG; QIAO, LIXIN
To: AVILA THERAPEUTICS, INC.
Reel/Frame 024145/0455 →
Continuity (5)
Provisional Application
61076450
· Jun 27, 2008
Provisional Application
61148388
· Jan 29, 2009
Provisional Application
61170874
· Apr 20, 2009