Biodegradable medical devices with enhanced mechanical strength and pharmacological functions
View Patent ↗The present invention is directed to a medical device, specifically a prosthesis which utilizes a novel class of blends between biodegradable polymers and bioceramics for medical device applications allowing one to capitalize on the biodegradable nature of these two distinct materials while enhancing the strength of these devices through the addition of various amounts of bioactive ceramic and glasses to biodegradable polymers. The blend may be fabricated into a medical device such as a stent or a distal protection device, and may incorporate various agents to enhance radioapacity and/or pharmacological function. In addition, the blend may be used as a coating to a medical device.
1. A medical device comprising an intravascular stent configured as a substantially tubular structure defining a longitudinal axis and having a plurality of longitudinally disposed bands, wherein each band defines a generally continuous wave along a line segment parallel to the longitudinal axis, and a plurality of links that maintain the plurality of bands in a tubular structure, wherein the stent is formed from an inorganic/organic blend including bioactive ceramic particles in an amount ranging from 15 to 25 percent of the blend by volume and biodegradable polymer particles in an amount ranging from 75 to 85 percent of the blend by volume, wherein each of the bioactive ceramic particles is equal to or less than 20 microns in size.
2. The medical device according to claim 1 , wherein the blend further comprises a radiopaque agent.
3. The medical device according to claim 1 , wherein the blend further comprises a pharmaceutical agent.