IP Library Granted Patent US 8,423,151
Granted Patent B2
US 8,423,151 · App. 11/926,057 · Granted Apr 16, 2013

Method and apparatus to provide safety checks for neural stimulation

Inventors: Robert Jay Greenberg (Los Angeles, CA); Kelly Hobart McClure (Simi Valley, CA); James Singleton Little (Saugus, CA); Rongqing Dai (Valencia, CA); Arup Roy (Valencia, CA); Richard Agustin Castro (Pasadena, CA); John Reinhold (Tarzana, CA); Kea-Tiong Tang (Temple City, CA); Sumit Yadav (Los Angeles, CA); Chunhong Zhou (Pasadena, CA); Dao Min Zhou (Saugus, CA); Pishoy Maksy (Sherman Oaks, CA)
Assignee: Second Sight Medical Products, Inc.
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Quick Facts
Patent No.
US 8,423,151
App. No.
11/926,057
Granted
Apr 16, 2013
Kind
B2
Abstract

In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue in not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes as continued use may result in neural and further electrode damage. Systems and stimulator control mechanisms to prevent damage to neural tissue.

Claims (13)

1. A method of stimulating retinal neural tissue comprising:

providing a neural stimulator including a plurality of electrodes suitable to stimulate retinal neural tissue;

providing a biphasic square wave pulse to each electrode;

calculating capacitive impedance by a first derivative of the voltage across a stimulation pulse;

testing the impedance of all electrodes by obtaining voltage measurements from all electrodes in response to said square wave pulses;

recording changes of capacitive impedance over time derived from said voltage measurements; and

determining lifting of electrodes based on changes of a capacitive component of said impedance by considering phase shifts in said changes of impedance over time;

wherein the changes of the capacitive component are computed based on a phase difference derived from a difference between a resultant voltage waveform obtained from the voltage measurements and a baseline voltage waveform without phase shifts derived from said voltage measurements.

2. The method according to claim 1 , further comprising discontinuing stimulation on said lifted electrodes.

3. The method of claim 1 , wherein the changes of the capacitive impedance are computed in part based on a phase difference derived from a difference between an area under a curve of the resultant voltage waveform and the baseline voltage waveform without phase shifts.

4. The method of claim 1 , wherein the changes of the capacitive impedance are computed in part based on a phase difference derived from a difference between an area under a curve of a first derivative of the resultant voltage waveform and the baseline voltage waveform without phase shifts.

5. The method of claim 1 , wherein the baseline voltage waveform is subtracted from the resultant voltage waveform.

6. The method of claim 1 , wherein determining lifting electrode further includes comparing the phase shift of anodic and cathodic phases of the baseline voltage waveform and the resultant voltage waveform.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 3, 2023
From: VIVANI MEDICAL, INC.
To: CORTIGENT, INC.
Reel/Frame 062589/0335 →
MERGER AND CHANGE OF NAME Recorded Dec 27, 2022
From: SECOND SIGHT MEDICAL PRODUCTS, INC.; VIVANI MEDICAL, INC.
To: VIVANI MEDICAL, INC.
Reel/Frame 062230/0446 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 24, 2008
From: GREENBERG, ROBERT JAY; MCCLURE, KELLY HOBART; LITTLE, JAMES SINGLETON; DAI, RONGQING; ROY, ARUP; CASTRO, RICHARD AGUSTIN; REINHOLD, JOHN; TANG, KEA-TIONG; YADAV, SUMIT; ZHOU, CHUNHONG; ZHOU, DAO MIN; MAKSY, PISHOY
To: SECOND SIGHT MEDICAL PRODUCTS, INC.
Reel/Frame 020420/0921 →
Continuity (2)
Division 11413771 · Apr 28, 2006
Related Publication 20080046041A1 · Feb 21, 2008