Granted Patent
B2
US 8,435,510 · App. 12/672,491 · Granted May 7, 2013
Platelet derived growth factor receptor supports cytomegalovirus infectivity
Assignee:
Sutter West Bay Hospitals
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Abstract
The disclosure relates generally to compositions and methods useful for inhibiting the infection and propagation of viral particles, particularly members of the Herpesviridae family, and more particularly to cytomegalovirus (CMV).
Claims (4)
1. A method for inhibiting HCMV infection comprising administering a therapeutically effective amount of a composition to a subject, wherein said composition comprises an antibody that binds to the PDGFRα receptor, inhibits PDGFRα receptor activation and inhibits HCMV entry.
2. The method of claim 1 , wherein the antibody is a monoclonal antibody.
3. The method of claim 1 , wherein the antibody is IMC-3G3.
4. The method of claim 1 , wherein the composition further comprises a pharmaceutically acceptable carrier.
Assignments (2)
CHANGE OF NAME
Recorded Apr 27, 2016
From: SUTTER WEST BAY HOSPITALS
To: SUTTER BAY HOSPITALS
Reel/Frame 038542/0160 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 28, 2010
From: COBBS, CHARLES; SOROCEANU, LILIANA
To: SUTTER WEST BAY HOSPITALS
Reel/Frame 025056/0101 →
Continuity (2)
Provisional Application
60954612
· Aug 8, 2007