Dosage form for hormonal contraception
A dosage form for hormonal contraception containing a given number of hormone-containing daily units and a given number of hormone-free daily units for daily, oral administration, where the hormone-containing daily units each contain at most the minimum effective daily amount of folic acid for women and the hormone-free daily units contain at least a multiple of this amount up to the maximum permissible amount of folic acid for women.
1. A hormonal contraceptive dosage form for uninterrupted daily oral administration to women, said dosage form comprising hormone-containing daily units and hormone-free daily units, wherein each of the hormone-containing daily units comprises folic acid in a daily amount of from between about 5 to 200 μg and a combination of an oestrogen and a gestagen, and each of the hormone-free daily units comprises folic acid in a daily amount of greater than 200 μg up to the maximum permissible amount of folic acid for women.
2. A dosage form according to claim 1 , wherein the hormone-free daily units each comprises more than 200 μg and up to 5 mg of folic acid.
3. A dosage form according to claim 1 , wherein the hormone-containing daily units each comprises the same amount of folic acid and the hormone-free daily units likewise each comprises the same amount of folic acid.
4. A dosage form according to claim 1 , wherein the dosage form comprises at least 21 hormone-containing daily units and 7 to 3 hormone-free daily units.
5. A dosage form according to claim 4 , wherein the number of hormone-containing daily units is sufficient for administration for a maximum of 2 years, and the number of hormone-free daily units is sufficient for administration for to 7 to 3 days.
6. A dosage form according to claim 4 , comprising up to 730 hormone-containing daily units and 7 to 3 hormone-free daily units.
7. A dosage form according to claim 4 , which comprises 21 to 25 hormone-containing daily units and 7 to 3 hormone-free daily units.
8. A dosage form according to claim 4 , which comprises 42 to 52 hormone-containing daily units and 7 to 3 hormone-free daily units.
9. A dosage form according to claim 4 , which comprises 77 to 193 hormone-containing daily units and 7 to 3 hormone-free daily units.
10. A dosage form according to claim 1 , wherein the number of hormone-containing daily units corresponds to a monophasic contraceptive.
11. A kit comprising at least one dosage form for hormonal contraception according to claim 1 .
12. A kit according to claim 11 , wherein the kit comprises a plurality of dosage forms.
13. A dosage form according to claim 6 , wherein the dosage form comprises up to 365 hormone-containing daily units and 7 to 3 hormone-free daily units.