IP Library Granted Patent US 8,593,141
Granted Patent B1
US 8,593,141 · App. 12/954,291 · Granted Nov 26, 2013

Magnetic resonance system and method employing a digital squid

Inventors: Masoud Radparvar (Yorktown Heights, NY); Alan M. Kadin (Princeton Junction, NJ)
Assignee: Hypres, Inc.
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Quick Facts
Patent No.
US 8,593,141
App. No.
12/954,291
Granted
Nov 26, 2013
Kind
B1
Abstract

A magnetic resonance system, comprising at least one SQUID, configured to receive a radio frequency electromagnetic signal, in a circuit configured to produce a pulsatile output having a minimum pulse frequency of at least 1 GHz which is analyzed in a processor with respect to a timebase, to generate a digital signal representing magnetic resonance information. The processor may comprise at least one rapid single flux quantum circuit. The magnetic resonance information may be image information. A plurality of SQUIDs may be provided, fed by a plurality of antennas in a spatial array, to provide parallel data acquisition. A broadband excitation may be provided to address a range of voxels per excitation cycle. The processor may digitally compensate for magnetic field inhomogeneities.

Claims (31)

1. A magnetic resonance imaging system, comprising a plurality of SQUIDs, each being configured to receive a radio frequency electromagnetic signal, and provided within a circuit configured to produce a pulsatile output having a minimum pulse frequency of at least 1 GHz which is analyzed in a digital processor with respect to a timebase, to generate a digital signal representing magnetic resonance image information derived from an object under examination,

wherein the processor receives a set of outputs from each of a plurality of SQUIDs, each respective SQUID responds to a respective antenna having a respectively different spatial placement, with respect to the object-under-examination.

2. The magnetic resonance imaging system according to claim 1 , wherein the digital processor comprises at least one rapid single flux quantum circuit.

3. The magnetic resonance imaging system according to claim 1 , wherein the radio frequency electromagnetic signal is received from a coil in close proximity to an object-under-examination within a magnetic field, and wherein the magnetic resonance image information is presented as spatial data.

4. The magnetic resonance imaging system according to claim 1 , wherein the digital processor is configured to digitally compensate for an inhomogeneous magnetic field.

5. The magnetic resonance imaging system according to claim 1 , wherein the digital processor is further configured to define a radio frequency excitation signal for addressing volumetric regions within a magnetic field.

6. The magnetic resonance imaging system according to claim 1 , wherein the digital processor defines a broadband radio frequency excitation signal for addressing at least one of a spatial range of volumetric regions and a plurality of different magnetically resonant isotopes.

7. The magnetic resonance imaging system according to claim 1 , wherein the digital processor receives the pulsatile output of the plurality of SQUIDs and decimates in time to produce a signal representation of each respective pulsatile output having an update rate less than the pulse frequency of the respective pulsatile output and a data representation at each update of greater than 1 bit.

8. A magnetic resonance digital system, comprising:

at plurality of SQUIDs, each being configured to receive a radio frequency electromagnetic signal, and being provided in a respective circuit configured to produce a pulsatile output having a minimum pulse frequency of at least 1 GHz which is analyzed in a digital processor with respect to a timebase, to generate a respective digital signal representing magnetic resonance information; with respect to an object-under-examination; and

a plurality of antennas, distributed in space, the antennas each feeding a respective one of the plurality of SQUIDs, each respective digital signal representing magnetic resonance information from a space proximate to a respective antenna.

9. The magnetic resonance imaging system according to claim 1 , wherein each of the plurality of SQUIDs is configured to represent in its pulsatile output a radio frequency magnetic field comprising frequencies of at least 100 kHz.

10. The magnetic resonance imaging system according to claim 1 , wherein signals from a plurality of antennas are multiplexed and presented to a common SQUID.

11. The magnetic resonance imaging system according to claim 1 , wherein signals from the plurality of SQUIDs are multiplexed into a composite digital signal, presented for analysis by the digital processor.

12. A magnetic resonance digital method, comprising:

providing a plurality of SQUIDs, each SQUID responding to a radio frequency electromagnetic signal from a respective antenna having a respectively different spatial placement, with respect to an object-under-examination, and being disposed in a circuit which produces a pulsatile output having a minimum pulse frequency of at least 1 GHz;

analyzing the pulsatile output of each respective SQUID with respect to a timebase in an automated digital processor; and

generating a digital signal representing magnetic resonance image information derived from the object under examination,

wherein the automated digital processor receives a set of outputs from each of a plurality of SQUIDs.

13. The magnetic resonance digital method according to claim 12 , wherein the automated digital processor comprises at least one rapid single flux quantum circuit.

14. The magnetic resonance digital method according to claim 12 , further comprising outputting an image representation of the magnetic resonance image information.

15. The magnetic resonance digital method according to claim 12 , wherein the analyzing further comprising digitally compensating for an inhomogeneous magnetic field.

16. The magnetic resonance digital method according to claim 12 , wherein the generating further comprising generating a radio frequency excitation signal for addressing volumetric regions within a magnetic field.

17. The magnetic resonance imaging method according to claim 12 , wherein the generating further comprising generating a broadband radio frequency excitation signal.

18. The magnetic resonance imaging method according to claim 12 , wherein the generating further comprising decimating in time to produce a signal representation having an update rate less than the pulse frequency of the pulsatile output and a data representation at each update of greater than 1 bit.

19. The magnetic resonance imaging method according to claim 12 , wherein the SQUID is configured to represent in its pulsatile output a radio frequency magnetic field comprising frequencies of at least 100 kHz.

20. A magnetic resonance imaging method, comprising:

receiving a radio frequency electromagnetic signal, in a circuit comprising a plurality of SQUIDs, each of which produces a pulsatile output having a minimum pulse frequency of at least 1 GHz;

analyzing the pulsatile output of each respective SQUID with respect to a timebase in an automated digital processor;

generating a digital signal representing magnetic resonance image information; and

providing a plurality of antennas, distributed in space to receive signals from an object-under-examination, the antennas each feeding a respective one of the plurality of SQUIDs, each SQUID forming part of a circuit configured to produce the pulsatile output having a minimum pulse frequency of at least 1 GHz which is analyzed in the automated digital processor with respect to the timebase, to generate a digital signal representing magnetic resonance information from a space proximate to the antennas.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 31, 2019
From: HYPRES, INC.
To: THE JOHNSON REVOCABLE TRUST DATED 6/25/2003
Reel/Frame 048210/0239 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 24, 2010
From: RADPARVAR, MASOUD; KADIN, ALAN M.
To: HYPRES, INC.
Reel/Frame 025421/0178 →
Continuity (1)
Provisional Application 61264032 · Nov 24, 2009