Method and a system for registering a 3D pre-acquired image coordinates system with a medical positioning system coordinate system and with a 2D image coordinate system

1. Method for registering a three dimensional (3D) coordinate system with a Medical Positioning System (MPS) coordinate system and a two dimensional (2D) coordinate system, the method comprising:

acquiring a 2D image of a volume of interest, said volume of interest including an organ within the body of a patient, said 2D image being associated with said 2D coordinate system;

acquiring MPS points within said organ, said MPS points being associated with said MPS coordinate system, said MPS coordinate system being registered with said 2D coordinate system;

extracting a 3D image model of said organ from a pre acquired 3D image of said volume of interest, said pre acquired 3D image and said 3D image model being associated with said 3D coordinate system;

estimating a volumetric model of said organ according to said acquired MPS points; and

registering said 3D coordinate system with said MPS coordinate system by matching said extracted 3D image model with said estimated volumetric model,

wherein said 2D coordinate system, said 3D coordinate system, and said MPS coordinate system are three different coordinate systems.

2. The method of claim 1 , further comprising pre-acquiring said 3D image before extracting said 3D image model.

3. The method of claim 2 , wherein said 3D image is acquired before said 2D image is acquired.

4. The method of claim 1 , wherein each of said MPS points, said 2D image, and said pre-acquired 3D image is associated with a respective organ timing signal activity state.

5. The method of claim 4 , wherein said organ timing signal represents an activity state in a cycle of said organ.

6. The method of claim 4 , wherein said organ timing signal comprises an electrocardiogram signal.

7. The method of claim 1 , wherein said 2D image comprises an x-ray image.

8. The method of claim 1 , wherein said 3D image comprises at least one of a CT image, an MRI image, a PET image, and a 3D ultrasound image.

9. The method of claim 1 , wherein said extracting comprises segmenting said 3D image.

10. System for registering a three dimensional (3D) coordinate system with a Medical Positioning System (MPS) coordinate system and a two dimensional (2D) coordinate system, the system including a medical imaging system for acquiring a 2D image of a volume of interest within the body of a patient, and a 3D medical images database for storing a pre-acquired 3D image of said volume of interest, the 2D image being associated with the 2D coordinate system, the pre-acquired 3D image being associated with the 3D coordinate system, the volume of interest including an organ, the system comprising:

an MPS associated with said MPS coordinate system, said MPS comprising:

a plurality of MPS transmitters for generating an electromagnetic field; and

an MPS sensor for acquiring a plurality of MPS points within said at least one organ, said MPS sensor being associated with said MPS coordinate system, said MPS coordinate system being registered with said 2D coordinate system; and

a coordinate systems registration processor coupled with said MPS, with said medical imaging system, and with said 3D medical images database, said coordinate systems registration processor configured to:

extract a 3D image model of said organ from the pre-acquired 3D image of said organ;

estimate a volumetric model of said organ according to said MPS points; and

register said 3D coordinate system with said MPS coordinate system by matching said 3D image model with said volumetric model,

wherein said 2D coordinate system, said 3D coordinate system, and said MPS coordinate system are three different coordinate systems.

11. The system of claim 10 , wherein said MPS sensor is a first MPS sensor, wherein one of said MPS transmitters and a second MPS sensor is coupled with and moves with said medical imaging system.

12. The system of claim 10 , wherein said coordinate systems registration processor is configured to extract said 3D image model by segmenting the 3D image of said organ.

13. The system of claim 10 , wherein each of said MPS points, the 2D image, and the pre-acquired 3D image are all associated with a respective organ timing signal activity state of said organ.

14. The system of claim 13 , wherein said organ timing signal is an electrocardiogram signal.

15. The system of claim 10 , wherein said MPS points comprise a trace and said coordinate systems registration processor is configured to estimate said volumetric model according to said trace.

16. The system claim 10 , wherein said MPS sensor is configured to detect a magnetic portion of said electromagnetic field.

17. Method for registering a three dimensional (3D) coordinate system with a Medical Positioning System (MPS) coordinate system, the method comprising:

acquiring MPS points within an organ within a volume of interest of the body of a patient, said MPS points being associated with said MPS coordinate system;

extracting a 3D image model of said organ from a pre-acquired 3D image of said volume of interest, said pre-acquired 3D image and said 3D image model being associated with said 3D coordinate system;

estimating a volumetric model of said organ according to said acquired MPS points; and

registering said 3D coordinate system with said MPS coordinate system by matching said extracted 3D image model with said estimated volumetric model.

18. The method of claim 17 , further comprising pre-acquiring said 3D image before extracting said 3D image model.

19. The method of claim 17 , wherein said MPS points comprise a trace and said estimating comprises estimating said volumetric model according to said trace.

20. The method of claim 17 , wherein said organ comprises the heart of said patient.