Syringe for prefilled syringe

1. A syringe for prefilled syringe comprising:

a plunger in which a gasket is attached to a top; and

a syringe barrel in which the plunger is slidably stored,

wherein the syringe barrel includes an inner wall subjected to surface modification with a polymer containing zwitterion,

wherein the polymer containing zwitterion is at least one selected from the group consisting of the following chemical formula (2) and chemical formula (3):

wherein X 1 , X 2 , Y 1 and Y 2 are each independent;

X 1 and X 2 are hydrogen atom or methyl group;

Y 1 and Y 2 are —C(O)O— or —C(O)NH—;

n1 and n2 which are a polymerization degree are each independent;

n1 is an integer of 1 to 100,000;

n2 is an integer of 1 to 100,000; and

R 1 and R 2 each independently represent a betaine group shown in the following formula (1):

*-A 1 -L-A 2   formula (1)

wherein A 1 and A 2 are each independent;

A 1 is a quaternary ammonium ion ((—(R x )—N(R y ) 2 (R z )—) + ), and wherein R x represents an alkylene group having 1 to 6 carbon atoms, R y independently represents an alkyl group having 1 to 6 carbon atoms, and R z represents a single bond binding to linker group;

A 2 is at least one selected from the group consisting of carboxylate ion (—COO − ), phosphate ion (—OPO 3 2− ), sulfate ion (—OSO 3 − ), and sulfonate ion (—SO 3 − );

L represents an alkylene group having 1 to 6 carbon atoms;

wherein X 3 and Y 3 are each independent;

X 3 is hydrogen atom or methyl group;

Y 3 is —C(O)O— or —C(O)NH—;

n1 which is a polymerization degree is an integer of 1 to 100,000; and

R 3 represents betaine group shown in the above-described formula (1).

2. The syringe for prefilled syringe according to claim 1 , wherein the gasket comprises a surface subjected to surface modification with a polymer containing zwitterion.

3. The syringe for prefilled syringe according to claim 2 , wherein the following expression:

( a )≦( b )≦( c )

is met assuming that the chain length of a polymer containing zwitterion, with which surface modification is performed on the inner wall of the syringe barrel is a chain length (a); the chain length of a polymer containing zwitterion, with which surface modification is performed on a pressurization surface located in a top of the gasket in the gasket surface is a chain length (b); and the chain length of a polymer containing zwitterion, with which surface modification is performed on a gasket side surface contacting with the inner wall of the syringe barrel in the gasket surface is a chain length (c).

4. The syringe for prefilled syringe of claim 1 , wherein the formula (1) is either the following chemical formulae (A):

or the following chemical formula (B):

5. The syringe for prefilled syringe according to claim 1 , wherein the number average molecular weight of the polymer containing zwitterion is 200,000 to 800,000.