Nerve-penetrating apparatus and method for optical and/or electrical nerve stimulation of peripheral nerves
Apparatus and method for making and using devices that generate optical signals, and optionally also electrical signals in combination with one or more such optical signals, to stimulate (i.e., trigger) and/or simulate a sensory-nerve signal in nerve and/or brain tissue of a living animal (e.g., a human), for example to treat nerve damage in the peripheral nervous system (PNS) or the central nervous system (CNS) and provide sensations to stimulate and/or simulate “sensory” signals in nerves and/or brain tissue of a living animal (e.g., a human) to treat other sensory deficiencies (e.g., touch, feel, balance, visual, taste, or olfactory) and provide sensations related to those sensory deficiencies, and/or to stimulate (i.e., trigger) and/or simulate a motor-nerve signal in nerve and/or brain tissue of a living animal (e.g., a human), for example to control a muscle or a robotic prosthesis.
1. An apparatus comprising:
a plurality of laser-light sources configured to generate a plurality of laser-light signals, wherein the plurality of laser-light sources includes a first laser-light source that emits light having a first wavelength and a second laser-light source that emits light having the first wavelength;
one or more driver circuits that provide drive power required to operate the plurality of laser-light sources;
a control circuit operatively coupled to the driver circuits and configured to control emission of pulsed light from the first and second laser-light sources; and
a laser-light-delivery system that includes a first needle-like projection that has only one pointed end and is configured to deliver the plurality of laser light signals independently and non-diffusely from the first needle-like projection to each of a plurality of nerves within a peripheral nerve bundle of an animal in order to independently optically stimulate each of the plurality of nerves in the peripheral nerve bundle to trigger action potentials in the plurality of nerves, wherein the pointed end of the laser-light-delivery system is configured to be transversely implanted into the peripheral nerve bundle by penetrating the peripheral nerve bundle with the pointed end of the laser-light-delivery system, and wherein the first needle-like projection is operatively coupled to at least the first laser-light source and the second laser-light source.
2. The apparatus of claim 1 , wherein the plurality of laser-light sources includes a plurality of vertical-cavity-surface-emitting lasers (VCSELs) including a first VCSEL and a second VCSEL, wherein the plurality of VCSELs are arranged on the laser-light-delivery system such that when the laser-light-delivery system is transversely implanted into the peripheral nerve bundle the first VCSEL is located at a first transverse depth within the peripheral nerve bundle and the second VCSEL is located at a second transverse depth within the peripheral nerve bundle.
3. The apparatus of claim 2 , wherein the first needle-like projection is an only mechanical support for the laser-light-delivery system and the plurality of VCSELs are arranged as a one dimensional array along the first needle-like projection.
4. The apparatus of claim 2 , wherein the laser-light-delivery system includes a plurality of parallel needle-like projections including the first needle-like projection and a second needle-like projection and the VCSELs are arranged in a two-dimensional array such that some of the plurality of VCSELs are located on each of the plurality of parallel needle-like projections.
5. The apparatus of claim 2 , wherein the laser-light-delivery system includes the first needle-like projection and a second needle-like projection, wherein a first set of VCSELs are supported by the first needle-like projection and are configured to deliver the plurality of laser-light signals in a first radial direction into the plurality of nerves form within the peripheral nerve bundle, wherein a second set of plurality of VCSELs are supported by the second needle-like projection and are configured to deliver the plurality of laser-light signals in a second radial direction into the plurality of nerves from within the peripheral nerve bundle, and wherein the second radial direction is different than the first radial direction.
6. The apparatus of claim 2 , wherein VCSELs supported by the first needle-like projection are configured to deliver the plurality of laser-light signals in each of a plurality of radial directions into the peripheral nerve bundle.
7. The apparatus of claim 1 , wherein the plurality of laser-light sources includes a plurality of vertical-cavity-surface-emitting lasers (VCSELs), and wherein the laser-light-delivery system further includes:
a plurality of short optical fibers arranged in a plurality of needle-like bundles, each optical fiber extending from one of the plurality of VCSELs, wherein the plurality of needle-like bundles are each configured to be transversely inserted into the peripheral nerve bundle, and wherein the pointed end of the first needle-like projection is an end of one of the plurality of needle-like bundles.
8. A method comprising:
providing a laser-light-delivery system that includes a plurality of laser-light sources;
transversely implanting the laser-light-delivery system into a peripheral nerve bundle of an animal, the laser-light-delivery system including a first needle-like projection that has only one pointed end inserted into the peripheral nerve bundle, wherein the first needle-like projection is operatively coupled to at least a first laser-light source and a second laser-light source of the plurality of laser-light sources;
generating a plurality of pulsed laser-light signals from the plurality of laser-light sources including a first pulsed laser-light signal having a first wavelength and a second pulsed laser-light signal having the first wavelength; and
independently and non-diffusely delivering the plurality of pulsed laser-light signals through the first needle-like projection of the laser-light-delivery system to each of a plurality of nerves within the peripheral nerve bundle, and, based on the plurality of pulsed laser-light signals, independently optically triggering an action potential in each of the plurality of nerves in the peripheral nerve bundle.
9. The method of claim 8 , wherein the plurality of laser-light sources includes a plurality of vertical-cavity-surface-emitting lasers (VCSELs) including a first VCSEL and a second VCSEL, the method further comprising:
mechanically supporting the plurality of VCSELs on the laser-light-delivery system such that the first VCSEL is located at a first transverse depth within the peripheral nerve bundle and the second VCSEL is located at a second transverse depth within the peripheral nerve bundle.
10. The method of claim 9 , wherein the first needle-like projection is an only needle-like projection for the laser-light-delivery system, and wherein the mechanically supporting of the plurality of VCSELs includes arranging the plurality of VCSELs as a one-dimensional array along the first needle-like projection.
11. The method of claim 9 , wherein the laser-light-delivery system includes a plurality of parallel needle-like projections including the first needle-like projection and a second needle-like projection, and wherein the mechanically supporting of the plurality of VCSELs includes arranging the plurality of VCSELs as a two-dimensional array such that some of the plurality of VCSELs are located on each of the plurality of parallel needle-like projections.
12. The method of claim 9 , further comprising:
providing a plurality of needle-like projections including the first needle-like projection and a second needle-like projection that has only one pointed end, wherein the independently delivering of the plurality of laser-light signals includes delivering laser-light signals from a first subset of the plurality of VCSELs located on the first needle-like projection in a first direction and delivering the plurality of laser-light signals from a second subset of the plurality of VCSELs located on the second needle-like projection in a second direction.
13. The method of claim 8 , wherein the plurality of laser-light sources includes a plurality of vertical-cavity-surface-emitting lasers (VCSELs) including a first VCSEL and a second VCSEL, the method further comprising:
providing a plurality of short optical fibers configured to be inserted into the peripheral nerve bundle, wherein the plurality of short optical fibers are arranged in a plurality of needle-like bundles, wherein the pointed end of the first needle-like projection is an end of one of the plurality of needle-like bundles; and
extending an optical fiber of the plurality of short optical fibers from each one of the plurality of VCSELs into the laser-light-delivery system.
14. The method of claim 8 , wherein the laser-light-delivery system includes a plurality of vertical-cavity-surface-emitting lasers (VCSELs), wherein the independently delivering of the plurality of laser-light signals includes emitting laser-light signals from the laser-light-delivery system in a plurality of non-parallel directions.
15. The method of claim 8 , further comprising:
delivering an electrical current from a plurality of driver circuits at one end of an electrical cable to a plurality of lasers at another distal end of the electrical cable; and
using the electrical current to generate the plurality of laser-light signals from the plurality of lasers.
16. An apparatus comprising:
a plurality of laser-light sources configured to generate a plurality of laser-light signals, wherein the plurality of laser-light sources includes a first laser-light source that emits light having a first wavelength and a second laser-light source that emits light having the first wavelength; and
means for independently and non-diffusely delivering the plurality of laser-light signals to each of a plurality of nerves within a peripheral nerve bundle of an animal in order to independently optically stimulate each of the plurality of nerves in the peripheral nerve bundle to trigger action potentials in the plurality of nerves, wherein the means for delivering includes a first needle-like projection that has only one pointed end, wherein the first needle-like projection is operatively coupled to at least the first laser-light source and the second laser-light source, and wherein the means for delivering is configured to be transversely implanted into the peripheral nerve bundle by penetrating the peripheral nerve bundle with the pointed end of the means for delivering.
17. The apparatus of claim 16 , wherein the plurality of laser-light sources includes a plurality of vertical-cavity-surface-emitting lasers (VCSELs), wherein the plurality of VCSELs includes a first VCSEL and a second VCSEL, the apparatus further comprising:
means for mechanically supporting the plurality of VCSELs such that the first VCSEL is located at a first transverse depth within the peripheral nerve bundle and the second VCSEL is located at a second transverse depth within the peripheral nerve bundle.
18. The apparatus of claim 17 , wherein the means for mechanically supporting the plurality of VCSELs includes means for arranging the plurality of VCSELs as a one-dimensional array.
19. The apparatus of claim 17 , wherein the means for mechanically supporting the plurality of VCSELs includes means for arranging the plurality of VCSELs as a two-dimensional array.
20. The apparatus of claim 16 , wherein the plurality of laser-light sources includes a plurality of vertical-cavity-surface-emitting lasers (VCSELs), wherein the plurality of VCSELs includes a first VCSEL and a second VCSEL, wherein the means for delivering includes means for delivering the plurality of laser-light signals of a first subset of the plurality of VCSELs in a first radial direction and means for delivering the plurality of laser-light signals from a second subset of the plurality of VCSELs in a second radial direction.