Phospholipid drug analogs

Inventors: Roberto Maj (Bioggio, CH); Franco Pattarino (Tornio, IT); Emanuela Mura (Bioggio, CH); Alcide Barberis (Bioggio, CH)

Assignee: TELORMEDIX, SA

A61K39/39 A61K39/015 A61K39/04 A61K47/48053 A61K31/522 A61K31/685 C07F9/65616 A61K2039/55511

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Quick Facts

Patent No.: US 9,050,319
App. No.: 13/775,924
Granted: Jun 9, 2015
Kind: B2

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Abstract

Provided in some embodiments are compositions comprising a compound having a structure according to Formula A or Formula B: or a pharmaceutically acceptable salt, tautomer or hydrate thereof, where X 2 is a bond or linker, X 3 is bond or —PO 4 —, and X 1 , R 1 , R 2 , R 3 , and n are described herein. Also provided in some embodiments are methods for making and using such compounds and compositions.

Claims (4)

1. A composition comprising a compound having a structure:

2. The composition of claim 1 , which further comprises an antigen.

3. The composition of claim 1 , which comprises a vaccine.

4. A method for inducing an immune response in a subject, comprising administering to the subject a composition of claim 1 .

Assignments (9)

PATENT SECURITY AGREEMENT Recorded Mar 18, 2024

From: UROGEN PHARMA LTD.

To: BIOPHARMA CREDIT PLC

Reel/Frame 066805/0346 →

PATENT SECURITY AGREEMENT Recorded Aug 18, 2023

From: UROGEN PHARMA LTD.