IP Library Granted Patent US 9,080,998
Granted Patent B2
US 9,080,998 · App. 13/297,853 · Granted Jul 14, 2015

Reagent store

Inventors: Paul Frank (Ennetbuergen, CH); Andreas Gisler (Thalwil, CH); Robert Huesler (Root, CH); Rolf Knobel (Rotkreuz, CH); Markus Rinderknecht (Adligenswil, CH)
Assignee: Roche Molecular Systems, Inc.
G01N35/1002G01N2035/00435G01N2035/00673G01N2035/00772G01N2035/00811
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Quick Facts
Patent No.
US 9,080,998
App. No.
13/297,853
Granted
Jul 14, 2015
Kind
B2
Abstract

An automated analyzer with an on-board fridge for long-term cooling of reagents, and a method for isolating and analyzing an analyte comprising long-term cooling of reagents.

Claims (14)

1. A method of providing reagent cassettes to an analytical system comprising the steps of:

a) loading a plurality of reagent cassettes onto a drawer of a stacker unit, said reagent cassettes include at least one RFID tag for reading and writing information related to time said reagent cassette is onboard the analytical system, the at least one RFID tag including a decrementing time counter;

b) identifying said reagent cassettes using an RFID reader;

c) automatically transferring said reagent cassettes from said drawer into a closed reagent store by an elevator comprising a Y-handler and a Z-axis into said reagent store;

d) positioning said reagent cassettes within said reagent store;

e) transferring instructions from a control unit to said reagent store, wherein said instructions specify which reagent cassettes are required by the analytical system;

f) removing a reagent cassette from the reagent store using said elevator comprising a Y-handler and a Z-axis and triggering the decrementing time counter to start to decrementally count during the time the reagent cassette is outside of the reagent store to determine the on-board time;

g) transporting said reagent cassette with said elevator to a station for presenting said reagent cassette to the analytical system, said station being located on a processing plate;

h) returning said reagent cassette to said reagent store when the on-board time is less than a preset value and stopping the decrementing counter or transferring said reagent cassette to a waste station when the on-board time exceeds a preset value.

2. The method of claim 1 , wherein steps b) to h) are automated.

3. The method according to claim 1 , wherein said reagent store is cooled by an active cooling unit.

4. The method of claim 3 , wherein the speed of the decrementing time counter is increased with increasing temperature.

5. The method according to claim 1 , wherein said positioning of said reagent cassettes within said reagent store is performed by the elevator.

6. The method of claim 1 , wherein reagents are transferred from said cassette held in said station for presenting said cassette to at least one receptacle by a pipetting device.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 7, 2012
From: FRANK, PAUL; GISLER, ANDREAS; HUESLER, ROBERT; KNOBEL, ROLF; RINDERKNECHT, MARKUS
To: ROCHE DIAGNOSTICS AG
Reel/Frame 027666/0314 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 7, 2012
From: ROCHE DIAGNOSTICS AG
To: ROCHE MOLECULAR SYSTEMS, INC.
Reel/Frame 027666/0387 →
Priority Claims (1)
EP 10192034 · Nov 22, 2010 · regional
Continuity (1)
Related Publication 20120294766A1 · Nov 22, 2012