Granted Patent
B2
US 9,434,700 · App. 14/521,909 · Granted Sep 6, 2016
Inhibitors of the fibroblast growth factor receptor
Inventors:
Neil Bifulco, Jr. (Sudbury, MA); Lucian V. DiPietro (Gloucester, MA); Brian L. Hodous (Cambridge, MA); Chandrasekhar V. Miduturu (Cambridge, MA)
C07D239/84C07D235/30C07D401/04C07D401/12C07D403/12C07D403/14C07D405/12C07D409/12C07D471/04C07D475/00
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Abstract
Described herein are inhibitors of FGFR-4, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions.
Claims (4)
1. A compound or pharmaceutically acceptable salt thereof, wherein the compound is:
2. A pharmaceutical composition comprising the compound of claim 1 or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
3. A compound or pharmaceutically acceptable salt thereof, wherein the compound is:
4. A pharmaceutical composition comprising the compound of claim 3 or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier.
Assignments (4)
RELEASE OF SECURITY INTEREST (REEL/FRAME NUMBER 060616/0923)
Recorded Jul 23, 2025
From: TAO TALENTS, LLC
To: BLUEPRINT MEDICINES CORPORATION
Reel/Frame 072193/0847 →
SECURITY INTEREST
Recorded Jul 8, 2022
From: BLUEPRINT MEDICINES CORPORATION
To: TAO TALENTS, LLC
Reel/Frame 060616/0923 →
ASSIGNEE CHANGE OF ADDRESS
Recorded Jul 6, 2018
From: BLUEPRINT MEDICINES CORPORATION
To: BLUEPRINT MEDICINES CORPORATION
Reel/Frame 046495/0375 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 13, 2016
From: BIFULCO, JR., NEIL, JR.; DIPIETRO, LUCIAN V.; HODOUS, BRIAN L.; MIDUTURU, CHANDRASEKHAR V.
To: BLUEPRINT MEDICINES CORPORATION
Reel/Frame 039145/0309 →
Continuity (3)
Provisional Application
61927782
· Jan 15, 2014
Provisional Application
61895472
· Oct 25, 2013