IP Library Granted Patent US 9,545,302
Granted Patent B2
US 9,545,302 · App. 14/084,896 · Granted Jan 17, 2017

Skin printing and auto-grafting

Inventors: David Tumey (Gaithersburg, MD); Sandra Berriman (Gaithersburg, MD)
Assignee: DermaGenesis LLC
A61F2/105A61L27/227A61L27/362A61L27/3604A61L27/3691A61L27/60B29C67/0055B29C67/0088B33Y10/00B33Y50/00C12N5/0625C12N5/0698A61F2210/0004A61F2230/0017A61F2240/002A61K35/36A61L2300/412A61L2300/64A61L2430/34C12N2513/00
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Quick Facts
Patent No.
US 9,545,302
App. No.
14/084,896
Granted
Jan 17, 2017
Kind
B2
Abstract

An apparatus and method for the production of substitute skin that advantageously reduces the amount of donor dermal cells needed from non-wound areas of a patient having a wound to be auto-grafted is reduced by using all of the harvested skin cells. A 3D printer is used to construct a wound graft product from the harvested skin cells without wasting any of the harvested skin cells. In a case of an irregularly shaped wound, wastage of harvested skin associated with trimming is avoided.

Claims (13)

1. A computerized skin printing system comprising;

a quantity of living donor skin cells harvested from a non-wound area of a patient having a to-be-treated wound or tissue defect;

a three-dimensional printer that processes the quantity of living donor skin cells, wherein the three-dimensional printer is under control of a controller connected to the three-dimensional printer;

an imaging device;

a sizing grid projected onto the wound or tissue defect while the imaging device is being operated;

a computer that performs steps of receiving a set of images taken by the imaging device of the wound or tissue defect of the patient and processing the imaged wound or tissue defect into a set of skin-printing instructions that are provided to the controller connected to the three-dimensional printer, and operating the three-dimensional printer to construct a customized skin graft product useable to be auto-grafted onto the wound or tissue defect of the patient.

2. The skin printing system of claim 1 , further comprising at least one syringe pump under control of the controller.

3. The skin printing system of claim 2 , wherein the at least one syringe pump contains the quantity of living donor skin cells harvested from the non-wound area.

4. The skin printing system of claim 1 , further comprising a surface onto which the three-dimensional printer prints a skin product.

5. The skin printing system of claim 4 , wherein the skin product printed onto the surface corresponds to a model generated by the computer from the set of wound images.

6. The skin printing system of claim 1 , further comprising a pump, and wherein skin cells in a syringe are pumped by the pump into the three-dimensional printer.

7. The skin printing system of claim 1 , wherein the computer digitizes a wound image and models the digitized image into a set of printing instructions.

8. The skin printing system of claim 4 , further comprising an agar plate comprising the surface onto which the three-dimensional printer prints the skin product.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 5, 2014
From: INNOVATIVE THERAPIES, INC.
To: DERMAGENESIS LLC
Reel/Frame 032351/0718 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 13, 2014
From: TUMEY, DAVID; BERRIMAN, SANDRA
To: INNOVATIVE THERAPIES, INC.
Reel/Frame 031951/0123 →
Continuity (1)
Related Publication 20150139960A1 · May 21, 2015