IP Library Granted Patent US 9,615,769
Granted Patent B2
US 9,615,769 · App. 14/099,034 · Granted Apr 11, 2017

Method to generate an RF excitation pulse to excite an arbitrarily shaped volume, method for targeted excitation of spins within a vessel, and method to create MR angiography images, and magnetic resonance system

Inventor: Hans-Peter Fautz (Forchheim, DE)
Assignee: Siemens Aktiengesellschaft
A61B5/055A61B5/004G01R33/48G01R33/4836G01R33/5635G01R33/56366
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Quick Facts
Patent No.
US 9,615,769
App. No.
14/099,034
Granted
Apr 11, 2017
Kind
B2
Abstract

In order to generate an RF excitation pulse together with a gradient curve to excite nuclear spins an arbitrarily shaped volume with a magnetic resonance system, a volume segment is prepared in which the volume is situated, such that only spins within the volume yield an MR signal portion in the subsequent detection of an MR signal. An MR signal is detected from the volume segment along a trajectory of k-space. At least one gradient for scanning k-space along the trajectory is switched during the detection. The RF excitation pulse is generated corresponding to the MR signal detected in a temporally inverted manner, and the gradient curve is generated corresponding to the temporally inverted curve of the at least one gradient to scan k-space.

Claims (89)

1. A method to generate a radio-frequency (RF) excitation pulse together with a gradient curve for a targeted excitation of nuclear spins in an arbitrarily shaped volume, comprising:

from a computerized control unit, operating a magnetic resonance (MR) data acquisition unit in which an examination volume is situated, to prepare a volume segment in said volume to cause only nuclear spins within said volume to contribute to an MR signal in a subsequent detection of said magnetic resonance signal;

from said control unit, operating said MR data acquisition unit to detect said MR signal from said volume segment while activating at least one gradient that causes data representing the detected magnetic resonance signal to be entered into an electronic memory organized as k-space, along a trajectory in k-space defined by said at least one gradient, said MR signal having an MR signal curve with respect to time and said at least one gradient having a gradient curve with respect to time; and

in said control unit, automatically generating said RF excitation pulse for said targeted excitation as an RF pulse having an RF pulse curve that is a temporal inversion of said MR signal curve, and generating said gradient curve for said targeted excitation as a gradient having a gradient curve that is a temporal inversion of the gradient curve of said at least one gradient activated during detection of said MR signal, and making an electronic signal available at an output of said control unit embodying said RF excitation pulse and said gradient curve for said targeted excitation in a form usable to operate said MR data acquisition unit to implement said targeted excitation.

2. A method as claimed in claim 1 comprising:

preparing said volume by saturating or inverting said nuclear spins in said volume segment; and detecting said MR signal by detecting MR signal contributions produced by nuclear spins in a flowing medium that have flowed into said volume after preparing said volume segment.

3. A method as claimed in claim 1 comprising generating said RF excitation pulse for said targeted excitation with a flip angle that is less than 30°.

4. A method as claimed in claim 1 comprising:

generating said RF excitation pulse for said targeted excitation with a flip angle that is greater than or equal to 30°; and

in said control unit, adapting said RF excitation pulse for said targeted excitation dependent on a magnitude of said flip angle and dependent on the detected MR signal in order to excite only nuclear spins in said volume.

5. A method as claimed in claim 1 wherein said MR data acquisition unit comprises multiple RF antennas, and wherein said method comprises:

detecting said MR signal with each of said RF antennas, thereby resulting in a plurality of respectively detected MR signals; and

in said control unit, generating said RF excitation pulse for said targeted excitation as a plurality of RF pulses to be respectively radiated by said multiple RF antennas, with each RF pulse to be radiated by each RF antenna being a temporal inversion of the respective MR signal detected by the respective RF antenna.

6. A method as claimed in claim 1 comprising:

in said control unit, determining said volume segment such that, outside of said volume, said volume segment comprises no additional volume having properties comparable to properties of said volume.

7. A method for targeted excitation of nuclear spins within a blood vessel, comprising:

from a computerized control unit, operating a magnetic resonance (MR) data acquisition unit in which an examination volume is situated, to prepare a volume segment in said volume to cause only nuclear spins within said volume to contribute to an MR signal in a subsequent detection of said MR signal;

from said control unit, operating said MR data acquisition unit to detect said MR signal from said volume segment while activating at least one gradient that causes data representing the detected MR signal to be entered into an electronic memory organized as k-space, along a trajectory in k-space defined by said at least one gradient, said MR signal having an MR signal curve with respect to time and said at least one gradient having a gradient curve with respect to time;

in said control unit, automatically generating said RF excitation pulse for said targeted excitation as an RF pulse having an RF pulse curve that is a temporal inversion of said MR signal curve, and generating said gradient curve for said targeted excitation as a gradient having a gradient curve that is a temporal inversion of the gradient curve of said at least one gradient activated during detection of said MR signal; and

from said control unit operating said MR data acquisition unit to implement said targeted excitation by radiating said RF excitation pulse and activating said gradient curve.

8. A method as claimed in claim 7 wherein said MR data acquisition unit comprises multiple RF antennas, and wherein said method comprises:

detecting said MR signal with each of said RF antennas, thereby resulting in a plurality of respectively detected MR signals;

in said control unit, generating said RF excitation pulse for said targeted excitation as a plurality of RF pulses to be respectively radiated by said multiple RF antennas, with each RF pulse to be radiated by each RF antenna being a temporal inversion of the respective MR signal detected by the respective RF antenna; and

radiating said plurality of RF pulses respectively from said multiple of RF antennas in said targeted excitation.

9. A method to generate a magnetic resonance (MR) angiography image of an examination subject, comprising:

from a computerized control unit, operating an MR data acquisition unit in which an examination volume is situated, to prepare a vessel in said volume to cause only nuclear spins within said vessel to contribute to an MR signal in a subsequent detection of said MR signal;

from said control unit, operating said MR data acquisition unit to detect said MR signal from said vessel while activating at least one gradient that causes data representing the detected MR signal to be entered into an electronic memory organized as k-space, along a trajectory in k-space defined by said at least one gradient, said MR signal having an MR signal curve with respect to time and said at least one gradient having a gradient curve with respect to time; and

in said control unit, automatically generating said RF excitation pulse for a subsequent targeted excitation of said vessel as an RF pulse having an RF pulse curve that is a temporal inversion of said MR signal curve, and generating said gradient curve for said targeted excitation of said vessel as a gradient having a gradient curve that is a temporal inversion of the gradient curve of said at least one gradient activated during detection of said MR signal;

from said control unit, operating said MR data acquisition unit by radiating said RF excitation pulse and activating said gradient curve to implement said targeted excitation of said vessel, and acquiring MR data following said targeted excitation; and

in a processor, reconstructing an angiographic image of said vessel from said MR data acquired following said targeted excitation.

10. A method as claimed in claim 9 wherein said MR data acquisition unit comprises multiple RF antennas, and wherein said method comprises:

detecting said MR signal with each of said RF antennas, thereby resulting in a plurality of respectively detected MR signals; and

in said control unit, generating said RF excitation pulse for said targeted excitation as a plurality of RF pulses to be respectively radiated by said multiple RF antennas, with each RF pulse to be radiated by each RF antenna being a temporal inversion of the respective MR signal detected by the respective RF antenna.

11. A magnetic resonance (MR) apparatus a radio-frequency (RF) excitation pulse together with a gradient curve for a targeted excitation of nuclear spins in an arbitrarily shaped volume, comprising:

an MR data acquisition unit;

a computerized control unit configured to operate the MR data acquisition unit in which an examination volume is situated, to prepare a volume segment in said volume to cause only nuclear spins within said volume to contribute to an MR signal in a subsequent detection of said magnetic resonance signal;

said control unit being configured to operate said MR data acquisition unit to detect said MR signal from said volume segment while activating at least one gradient that causes data representing the detected magnetic resonance signal to be entered into an electronic memory organized as k-space, along a trajectory in k-space defined by said at least one gradient, said MR signal having an MR signal curve with respect to time and said at least one gradient having a gradient curve with respect to time; and

said control unit being configured to automatically generate said RF excitation pulse for said targeted excitation as an RF pulse having an RF pulse curve that is a temporal inversion of said MR signal curve, and to generate said gradient curve for said targeted excitation as a gradient having a gradient curve that is a temporal inversion of the gradient curve of said at least one gradient activated during detection of said MR signal, and to make an electronic signal available at an output of said control unit embodying said RF excitation pulse and said gradient curve for said targeted excitation in a form usable to operate said MR data acquisition unit to implement said targeted excitation.

12. An apparatus as claimed in claim 11 wherein:

said MR data acquisition unit comprises multiple RF antennas;

said control unit is configured to operate said MR data acquisition unit to detect said MR signal with each of said RF antennas, thereby resulting in a plurality of respectively detected MR signals; and

said control unit being configured to generate said RF excitation pulse for said targeted excitation as a plurality of RF pulses to be respectively radiated by said multiple RF antennas, with each RF pulse to be radiated by each RF antenna being a temporal inversion of the respective MR signal detected by the respective RF antenna.

13. A magnetic resonance (MR) apparatus for targeted excitation of nuclear spins within a blood vessel, comprising:

an MR data acquisition unit;

a computerized control unit configured to operate an MR data acquisition unit in which an examination volume is situated, to prepare a volume segment in said volume to cause only nuclear spins within said volume to contribute to an MR signal in a subsequent detection of said MR signal;

said control unit being configured to operate said MR data acquisition unit to detect said MR signal from said volume segment while activating at least one gradient that causes data representing the detected MR signal to be entered into an electronic memory organized as k-space, along a trajectory in k-space defined by said at least one gradient, said MR signal having an MR signal curve with respect to time and said at least one gradient having a gradient curve with respect to time;

said control unit being configured to automatically generate said RF excitation pulse for said targeted excitation as an RF pulse having an RF pulse curve that is a temporal inversion of said MR signal curve, and to generate said gradient curve for said targeted excitation as a gradient having a gradient curve that is a temporal inversion of the gradient curve of said at least one gradient activated during detection of said MR signal; and

said control unit being configured to operate said MR data acquisition unit to implement said targeted excitation by radiating said RF excitation pulse and activating said gradient curve.

14. An apparatus as claimed in claim 13 wherein:

said MR data acquisition unit comprises multiple RF antennas;

said control unit is configured to operate said MR data acquisition unit to detect said MR signal with each of said RF antennas, thereby resulting in a plurality of respectively detected MR signals;

said control unit is configured to generate said RF excitation pulse for said targeted excitation as a plurality of RF pulses to be respectively radiated by said multiple RF antennas, with each RF pulse to be radiated by each RF antenna being a temporal inversion of the respective MR signal detected by the respective RF antenna; and

said control unit is configured to operate said MR data acquisition unit to radiate said plurality of RF pulses respectively from said multiple of RF antennas in said targeted excitation.

15. A magnetic resonance (MR) apparatus to generate an MR angiography image of an examination subject, comprising:

an MR data acquisition unit;

a computerized control unit configured to operate the MR data acquisition unit in which an examination volume is situated, to prepare a vessel in said volume to cause only nuclear spins within said vessel to contribute to an MR signal in a subsequent detection of said MR signal;

said control unit being configured to operate said MR data acquisition unit to detect said MR signal from said vessel while activating at least one gradient that causes data representing the detected MR signal to be entered into an electronic memory organized as k-space, along a trajectory in k-space defined by said at least one gradient, said MR signal having an MR signal curve with respect to time and said at least one gradient having a gradient curve with respect to time; and

said control unit being configured to automatically generate an RF excitation pulse for a subsequent targeted excitation of said vessel as an RF pulse having an RF pulse curve that is a temporal inversion of said MR signal curve, and to generate said gradient curve for said targeted excitation of said vessel as a gradient having a gradient curve that is a temporal inversion of the gradient curve of said at least one gradient activated during detection of said MR signal;

said control unit being configured to operate said MR data acquisition unit by radiating said RF excitation pulse and activating said gradient curve to implement said targeted excitation of said vessel, and acquiring MR data following said targeted excitation; and

a processor configured to reconstruct an angiographic image of said vessel from said MR data acquired following said targeted excitation.

16. An apparatus as claimed in claim 15 wherein:

said MR data acquisition unit comprises multiple RF antennas;

said control unit is configured to operate said MR data acquisition unit to detect said MR signal with each of said RF antennas, thereby resulting in a plurality of respectively detected MR signals; and

said control unit is configured to generate said RF excitation pulse for said targeted excitation as a plurality of RF pulses to be respectively radiated by said multiple RF antennas, with each RF pulse to be radiated by each RF antenna being a temporal inversion of the respective MR signal detected by the respective RF antenna.

17. A non-transitory, computer-readable data storage medium encoded with programming instructions, said storage medium being loaded into a computerized control and processing system of a magnetic resonance (MR) apparatus that also comprises an MR data acquisition unit, said programming instructions causing said computerized control and evaluation system to:

operate the magnetic MR data acquisition unit in which an examination volume is situated, to prepare a volume segment in said volume to cause only nuclear spins within said volume to contribute to an MR signal in a subsequent detection of said magnetic resonance signal;

operate said MR data acquisition unit to detect said MR signal from said volume segment while activating at least one gradient that causes data representing the detected magnetic resonance signal to be entered into an electronic memory organized as k-space, along a trajectory in k-space defined by said at least one gradient, said MR signal having an MR signal curve with respect to time and said at least one gradient having a gradient curve with respect to time; and

automatically generate an RF excitation pulse for a subsequent targeted excitation of said volume as an RF pulse having an RF pulse curve that is a temporal inversion of said MR signal curve, and generate said gradient curve for said targeted excitation as a gradient having a gradient curve that is a temporal inversion of the gradient curve of said at least one gradient activated during detection of said MR signal, and make an electronic signal available at an output of said control and evaluation system embodying said RF excitation pulse and said gradient curve for said targeted excitation in a form usable to operate said MR data acquisition unit to implement said targeted excitation.

18. A non-transitory, computer-readable data storage medium as claimed in claim 17 wherein said MR data acquisition unit comprises multiple RF antennas, and wherein said programming instructions cause said control and evaluation system to:

operate said MR data acquisition unit to detect said MR signal with each of said RF antennas, thereby resulting in a plurality of respectively detected MR signals; and

generate said RF excitation pulse for said targeted excitation as a plurality of RF pulses to be respectively radiated by said multiple RF antennas, with each RF pulse to be radiated by each RF antenna being a temporal inversion of the respective MR signal detected by the respective RF antenna.

19. A non-transitory, computer-readable data storage medium encoded with programming instructions, said storage medium being loaded into a computerized control and processing system of a magnetic resonance (MR) apparatus that also comprises an MR data acquisition unit, said programming instructions causing said computerized control and evaluation system to:

operate the MR data acquisition unit in which an examination volume is situated, to prepare a volume segment in said volume to cause only nuclear spins within said volume to contribute to an MR signal in a subsequent detection of said MR signal;

operate said MR data acquisition unit to detect said MR signal from said volume segment while activating at least one gradient that causes data representing the detected MR signal to be entered into an electronic memory organized as k-space, along a trajectory in k-space defined by said at least one gradient, said MR signal having an MR signal curve with respect to time and said at least one gradient having a gradient curve with respect to time;

automatically generate an RF excitation pulse for a subsequent targeted excitation of said volume as an RF pulse having an RF pulse curve that is a temporal inversion of said MR signal curve, and generating said gradient curve for said targeted excitation as a gradient having a gradient curve that is a temporal inversion of the gradient curve of said at least one gradient activated during detection of said MR signal; and

operate said MR data acquisition unit to implement said targeted excitation by radiating said RF excitation pulse and activating said gradient curve.

20. A non-transitory, computer-readable data storage medium as claimed in claim 19 wherein said MR data acquisition unit comprises multiple RF antennas, and wherein said programming instructions cause said control and evaluation system to:

operate said MR data acquisition unit to detect said MR signal with each of said RF antennas, thereby resulting in a plurality of respectively detected MR signals;

generate said RF excitation pulse for said targeted excitation as a plurality of RF pulses to be respectively radiated by said multiple RF antennas, with each RF pulse to be radiated by each RF antenna being a temporal inversion of the respective MR signal detected by the respective RF antenna; and

operate said MR data acquisition unit to radiate said plurality of RF pulses respectively from said multiple of RF antennas in said targeted excitation.

21. A non-transitory, computer-readable data storage medium encoded with programming instructions, said storage medium being loaded into a computerized control and processing system of a magnetic resonance (MR) apparatus that also comprises an MR data acquisition unit, said programming instructions causing said computerized control and evaluation system to:

operate the MR data acquisition unit in which an examination volume is situated, to prepare a vessel in said volume to cause only nuclear spins within said vessel to contribute to an MR signal in a subsequent detection of said MR signal;

operating said MR data acquisition unit to detect said MR signal from said vessel while activating at least one gradient that causes data representing the detected MR signal to be entered into an electronic memory organized as k-space, along a trajectory in k-space defined by said at least one gradient, said MR signal having an MR signal curve with respect to time and said at least one gradient having a gradient curve with respect to time; and

automatically generate an RF excitation pulse for a subsequent targeted excitation of said vessel as an RF pulse having an RF pulse curve that is a temporal inversion of said MR signal curve, and generate said gradient curve for said targeted excitation of said vessel as a gradient having a gradient curve that is a temporal inversion of the gradient curve of said at least one gradient activated during detection of said MR signal;

operate said MR data acquisition unit by radiating said RF excitation pulse and activating said gradient curve to implement said targeted excitation of said vessel, and acquiring MR data following said targeted excitation; and

reconstruct an angiographic image of said vessel from said MR data acquired following said targeted excitation.

22. A non-transitory, computer-readable data storage medium as claimed in claim 21 wherein said MR data acquisition unit comprises multiple RF antennas, and wherein said programming instructions cause said control and evaluation system to:

operate said MR data acquisition unit to detect said MR signal with each of said RF antennas, thereby resulting in a plurality of respectively detected MR signals; and

generate said RF excitation pulse for said targeted excitation as a plurality of RF pulses to be respectively radiated by said multiple RF antennas, with each RF pulse to be radiated by each RF antenna being a temporal inversion of the respective MR signal detected by the respective RF antenna.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE ASSIGNEE PREVIOUSLY RECORDED AT REEL: 066088 FRAME: 0256. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 17, 2024
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS HEALTHINEERS AG
Reel/Frame 071178/0246 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2023
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS HEALTHINEERS AG
Reel/Frame 066088/0256 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 30, 2017
From: SIEMENS AKTIENGESELLSCHAFT
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 042524/0682 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2014
From: FAUTZ, HANS-PETER
To: SIEMENS AKTIENGESELLSCHAFT
Reel/Frame 032321/0970 →
Priority Claims (1)
DE 10 2012 222 413 · Dec 6, 2012 · national
Continuity (1)
Related Publication 20140159722A1 · Jun 12, 2014