Prosthetic mitral valve with adjustable support
Disclosed is an implantable mitral valve having an adjustable support. The support comprises a plurality of pairs of adjacent struts joined at apexes and a plurality of anchors for tissue engagement. The implant is adjustable to a first, reduced diameter for transluminal navigation and delivery to the left atrium of a heart. The implant may then expand to a second, enlarged diameter for the step of embedding the anchors into tissue surrounding and/or including the mitral valve. The implant may then be adjusted to a third, intermediate diameter, pulling the tissue radially inwardly, thereby reducing the native mitral valve annulus and supporting the prosthetic mitral valve.
1. An implantable mitral heart valve, comprising:
a tubular body having a proximal end, a distal end and a central lumen extending therethrough, the tubular body dimensioned for positioning at least partially within a native mitral heart valve and attachment to tissue surrounding the native mitral heart valve;
the body comprising at least a first pair of adjacent struts joined at a proximally facing apex, and at least a second pair of adjacent struts joined at a distally facing apex;
a plurality of anchors on the body, the anchors including distally facing sharp ends configured to embed into tissue surrounding the native mitral heart valve;
a valve carried by the body to regulate blood flow through the central lumen; and
a moveable restraint carried by the tubular body and configured to at least partially surround a pair of adjacent struts and lock the proximally facing apex between the pair of adjacent struts at a desired angle, wherein the restraint is axially movable relative to the proximally facing apex along the first pair of struts toward the distal end.
2. An implantable mitral heart valve as in claim 1 , comprising bioprosthetic leaflets.
3. An implantable mitral heart valve as in claim 2 , wherein the leaflets comprise pericardial tissue.
4. An implantable mitral heart valve as in claim 1 , further comprising a plurality of connectors, for connecting the valve to the tubular body.
5. An implantable mitral heart valve as in claim 1 , wherein the moveable restraint comprises an aperture for receiving the pair of adjacent struts.
6. An implantable mitral heart valve as in claim 5 wherein the restraint comprises a collar.
7. An implantable mitral heart valve as in claim 6 wherein the collar comprises a threaded surface.
8. An implantable mitral heart valve as in claim 7 wherein the pair of adjacent struts comprises a threaded surface.
9. An implantable mitral heart valve as in claim 8 , wherein rotation of the anchors axially displaces the anchors with respect to the body.
10. An implantable mitral heart valve as in claim 6 wherein advancing the collar in an axial direction reduces the angle between the pair of struts thereby reshaping the implant body.
11. An implantable mitral heart valve as in claim 1 , wherein the restraint is configured to reversibly adjust the implant body radially within a working range.
12. An implantable mitral heart valve as in claim 1 , wherein the anchors are each rotatably carried by the body.
13. An implantable mitral heart valve as in claim 1 , wherein the anchors are configured to be retractable.
14. An implantable mitral heart valve as in claim 1 , wherein the implant body is configured to be reshaped such that a diameter at the proximal end is different from a diameter at the distal end.
15. An implantable mitral heart valve as in claim 1 , wherein the restraint is slidable axially along the pair of struts.
16. An implantable mitral heart valve as in claim 1 , wherein at least one of the plurality of anchors has a helical shape and rotating the anchor causes the anchor to extend into the tissue.
17. An implantable mitral heart valve as in claim 1 , comprising eight pairs of adjacent struts and eight apexes.
18. An implantable mitral heart valve as in claim 17 , comprising eight restraints.
19. An implantable mitral heart valve as in claim 17 , comprising eight anchors.
20. An implantable mitral heart valve as in claim 1 , wherein each strut in an adjacent pair of struts comprises a threaded surface.
21. An implant as in claim 1 , wherein the moveable restraint is non-circular.
22. An implant as in claim 1 , wherein the moveable restraint comprises a push clip.
23. An implantable mitral heart valve, comprising:
a tubular body having a proximal end, a distal end and a central lumen extending therethrough;
the body comprising at least a first pair of adjacent struts joined at a proximally facing apex, and at least a second pair of adjacent struts joined at a distally facing apex;
a plurality of helical anchors rotatably carried by the body, the anchors including distally facing sharp ends configured to embed into tissue surrounding the mitral valve;
a valve carried by the body to regulate blood flow through the central lumen; and
a moveable restraint surrounding a pair of adjacent struts and configured to lock the apex between the pair of adjacent struts at a desired angle, wherein the restraint is axially movable relative to the proximally facing apex along the first pair of struts toward the distal end.
24. An implantable mitral heart valve as in claim 23 , wherein the moveable restraint comprises an aperture for receiving the pair of adjacent struts.
25. An implant as in claim 23 , wherein the moveable restraint is non-circular.