Subunit immersion vaccines for fish
The present disclosure provides an immersion vaccine for fish comprising at least one isolated antigen, specifically a recombinant antigen, such as is F. psychrophilum and/or infectious pancreatic necrosis virus (IPNV).
1. An immersion vaccine for fish comprising at least one isolated antigen having the amino acid sequence of SEQ ID NO: 7.
2. The immersion vaccine of claim 1 , wherein the vaccine further comprises at least a second different isolated antigen.
3. The immersion vaccine of claim 2 , wherein the second isolated antigen is an infectious pancreatic necrosis virus (IPNV) antigen.
4. The immersion vaccine of claim 1 , further comprising at least one additional agent selected from the group consisting of Aeromonas hydrophilia, Aeromonas salmonicida, Pseudomonas fluorescens, Vibrio anguillarum, Vibrio salmonicida, Renibacterium salmoninarum , infectious haemopoietic necrosis virus (IHNV), infectious salmon anemia virus (ISAV), pancreas disease virus (PDV), salmon alphavirus (SAV), salmon poxvirus, and viral haemorrhagic septicemia virus (VHSV).
5. A method of immunizing a fish against Flavobacterium psychrophilum comprising administering to said fish an immunologically effective amount of the immersion vaccine of claim 1 .
6. An immersion vaccine for fish comprising at least one of: (a) the amino acid sequence of SEQ ID NO: 9; or (b) the amino acid sequence of SEQ ID NO: 7 and SEQ ID NO: 8.