IP Library Granted Patent US 9,632,040
Granted Patent B2
US 9,632,040 · App. 14/701,812 · Granted Apr 25, 2017

System and method for phase-contrast X-ray imaging using a multi-sector source grating

Inventor: Dan Stutman (Cockeysville, MD)
Assignee: THE JOHNS HOPKINS UNIVERSITY
G01N23/04A61B6/032A61B6/4035A61B6/4291A61B6/484A61B6/5205G01N23/046G01N23/20075G01N2223/33
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,632,040
App. No.
14/701,812
Granted
Apr 25, 2017
Kind
B2
Abstract

A differential phase contrast X-ray imaging system includes an X-ray illumination system, a beam splitter arranged in a radiation path of the X-ray illumination system, and a detection system arranged in a radiation path to detect X-rays after passing through the beam splitter.

Claims (26)

1. A method for phase contrast imaging of an object using an interferometer comprising a multi-sector source grating, a beam-splitter grating, and an analyzer grating, wherein the object is positioned between the beam-splitter grating and the analyzer grating, the method comprising:

directing an X-ray beam onto the multi-sector source grating, wherein each sector of the multi-sector source grating is offset by a predetermined amount;

obtaining multiple images during a single exposure by translating the object or the interferometer, wherein the multiple images have a different interferometer phasing; and

combining the multiple images that were obtained to produce a phase contrast image of the object.

2. The method according to claim 1 , wherein the multi-sector source grating has greater than three different sectors.

3. The method according to claim 1 , wherein the multiple images are acquired at different angles through the object.

4. The method according to claim 1 , wherein the interferometer has a length about 1.8 m.

5. The method according to claim 1 , wherein the analyzer grating has a thickness of about several tens of centimeters.

6. The method according to claim 1 , wherein the multiple images are obtained using a line detector or a slot scan detector separated by about 1 cm that is positioned behind the analyzer grating.

7. The method according to claim 1 , wherein the multiple images of the object are obtained at angular increments of about 0.3°.

8. The method according to claim 1 , wherein the multiple images comprises four images and an angular range between the four images is about 0.9°.

9. The method according to claim 1 , wherein the analyzer grating comprises multiple glancing angle gratings stacked in order to cover a length of a detector.

10. A device for phase contrast imaging of an object comprising:

an interferometer comprising a multi-sector source grating, a beam-splitter grating, and an analyzer grating, wherein the object is positioned between the beam-splitter grating and the analyzer grating;

an X-ray source operable to direct an X-ray bean onto the multi-sector source grating, wherein each sector of the multi-sector source grating is offset by a predetermined amount;

a translation mechanism operable to translate the object or the interferometer;

a detector operable to obtain multiple images of the object during a single exposure; and

a processor operable to combine the multiple images that were obtained to produce a phase contrast image of the object.

11. The device according to claim 10 , wherein the multi-sector source grating has greater than three different sectors.

12. The device according to claim 10 , wherein the multiple images are acquired at different angles through the object.

13. The device according to claim 10 , wherein the interferometer has a length about 1.8 m.

14. The device according to claim 10 , wherein the analyzer grating has a thickness of about several tens of centimeters.

15. The device according to claim 10 , wherein the detector is a line detector or a slot scan detector and the multiple images are obtained using the line detector or the slot scan detector separated by about 1 cm that is positioned behind the analyzer grating.

16. The device according to claim 10 , wherein the multiple images of the object are obtained at angular increments of about 0.3°.

17. The device according to claim 10 , wherein the multiple images comprises four images and an angular range between the four images is about 0.9°.

18. The device according to claim 10 , wherein the analyzer grating comprises multiple glancing angle gratings stacked in order to cover a length of the detector.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 1, 2015
From: STUTMAN, DAN
To: THE JOHNS HOPKINS UNIVERSITY
Reel/Frame 035544/0456 →
Continuity (2)
Provisional Application 61990831 · May 9, 2014
Related Publication 20150323478A1 · Nov 12, 2015