Systems and methods for processing analyte sensor data

1. A method for processing sensor data of a continuous analyte sensor implanted within a body, wherein the continuous analyte sensor measures glucose levels, and the measurements are processed via sensor electronics, comprising:

initializing the sensor, the sensor in electrical communication with the sensor electronics configured to receive and process sensor data by the sensor;

acquiring sensor data, using the sensor, to measure an analyte level in a body fluid over a first interval based on a first elapsed time since the sensor was implanted;

adjusting the acquired sensor data by applying, using the sensor electronics, a first set of time-dependent algorithmic functions to the sensor data associated with the first interval, wherein the first set of time-dependent algorithmic functions comprise a first boundary of acceptability, wherein the first boundary comprises a first drift rate of the sensitivity over time, wherein the first boundary comprises a first drift of the baseline over time;

acquiring further sensor data, using the sensor, to measure the analyte level in the body fluid over a second interval based on a second elapsed time since the sensor was implanted and after the first interval;

adjusting the acquired further sensor data by applying, by the sensor electronics, a second set of time-dependent algorithmic functions to the sensor data associated with the second interval, wherein the second set of time-dependent algorithmic functions comprise a second boundary of acceptability, wherein the second boundary comprises a second drift rate of the sensitivity over time, wherein the second boundary comprises a second drift of the baseline over time, thereby adapting the system to compensate for sensor drift of the sensor.

2. The method of claim 1 , wherein initializing the sensor comprises engaging the sensor electronics with a housing coupled with the sensor.

3. The method of claim 2 , wherein engagement of the sensor electronics with the housing is detected and initialization commences automatically upon detection of the engagement.

4. The method of claim 1 , further comprising determining whether the sensor has been previously used.

5. The method of claim 4 , wherein determining whether the sensor has been previously used comprises comparing a conversion function of the sensor with a conversion function of a previously removed sensor.

6. The method of claim 4 , wherein determining whether the sensor has been previously used comprises reading a raw signal of the sensor.

7. The method of claim 4 , wherein determining whether the sensor has been previously used comprises comparing a sensitivity and/or baseline of the sensor with a sensitivity and/or baseline of a previously removed sensor.

8. The method of claim 4 , wherein determining whether the sensor has been previously used comprises comparing a trend in a signal from the sensor with a trend in a signal from a previously removed sensor.

9. The method of claim 4 , wherein determining whether the sensor has been previously used comprises performing two or more independent tests and then determining a probability that the sensor has been previously used based upon results of the tests.

10. The method of claim 1 , wherein the first boundary comprises a first sensitivity value and the second boundary comprises a second sensitivity value.

11. The method of claim 1 , wherein the first boundary comprises a first baseline value and the second boundary comprises a second baseline value.

12. The method of claim 1 , wherein the first boundary delineates acceptable slopes and baselines of a conversion function and the second boundary delineates acceptable slopes and baselines of the conversion function.

13. The method of claim 1 , wherein the first and second set of time-dependent algorithmic functions comprise first and second parameters associated with a conversion function.

14. The method of claim 1 , wherein the first and second set of time-dependent algorithmic functions comprise first and second drift compensation functions.

15. The method of claim 14 , wherein the first and second drift compensation functions differ in the amount of drift compensation that they apply.

16. The method of claim 1 , wherein the first interval is predetermined prior to sensor insertion, and wherein applying the second set of time-dependent algorithmic functions is triggered in response to elapsing of the predetermined first interval.

17. The method of claim 1 , wherein the first and second sets of time-dependent algorithmic functions comprise different conversion functions used to convert the sensor data into calibrated sensor data.

18. The method of claim 1 , wherein the first and second sets of time-dependent algorithmic functions comprise different parameters applied to a conversion function used to convert the sensor data into calibrated sensor data.

19. The method of claim 1 , wherein the first and second set of time-dependent algorithmic functions are determined prior to sensor implantation.

20. The method of claim 1 , wherein the applying the second set of time-dependent algorithmic functions to the sensor data associated with the second interval comprises dynamically applying a priori information based on time since sensor implantation.

21. The method of claim 1 , wherein the applying the second set of time-dependent algorithmic functions to the sensor data associated with the second interval comprises dynamically adapting a parameter of the second set of time-dependent algorithmic functions based on a prior knowledge of time-based sensor behavior during implantation.

22. A continuous analyte monitoring system for processing sensor data of a continuous analyte sensor implanted within a body, wherein the analyte sensor measures glucose levels, and the measurements are processed via sensor electronics, comprising:

a sensor configured to be implanted within a body and acquire sensor data associated with analyte levels of a body fluid; and

the sensor electronics configured to receive and process the sensor data obtained by the sensor, the sensor electronics including a processor configured to

initialize the sensor,

process the sensor data acquired using the sensor to measure an analyte level in the body fluid over a first interval based on a first elapsed time since the sensor was implanted,

adjust the acquired sensor data by applying a first set of time-dependent algorithmic functions to the sensor data associated with the first interval, wherein the first set of time-dependent algorithmic functions comprise a first boundary of acceptability, wherein the first boundary comprises a first drift rate of the sensitivity over time, wherein the first boundary comprises a first drift of the baseline over time,

process further sensor data acquired using the sensor to measure the analyte level in the body fluid over a second interval based on a second elapsed time since the sensor was implanted and after the first interval,

adjust the acquired further sensor data by applying second set of time-dependent algorithmic functions to the sensor data associated with the second interval, wherein the second set of time-dependent algorithmic functions comprise a second boundary of acceptability, wherein the second boundary comprises a second drift rate of the sensitivity over time, wherein the second boundary comprises a second drift of the baseline over time, thereby adapting the system to compensate for sensor drift of the sensor.

23. The system of claim 22 , wherein initialization of the sensor commences automatically when the sensor electronics engages a housing with the sensor.

24. The system of claim 23 , wherein engagement of the electronics with the housing is detected and initialization commences automatically upon detection of the engagement.

25. The system of claim 22 , wherein the processor is further configured to determine whether the sensor has been previously used.

26. The system of claim 25 , wherein determining whether the sensor has been previously used comprises comparing a conversion function of the sensor with a conversion function of a previously removed sensor.

27. The system of claim 25 , wherein determining whether the sensor has been previously used comprises reading a raw signal of the sensor.

28. The system of claim 25 , wherein determining whether the sensor has been previously used comprises comparing a sensitivity and/or baseline of the sensor with a sensitivity and/or baseline of a previously removed sensor.

29. The system of claim 25 , wherein determining whether the sensor has been previously used comprises comparing a trend in a signal from the sensor with a trend in a signal from a previously removed sensor.

30. The system of claim 25 , wherein determining whether the sensor has been previously used comprises performing two or more independent tests and then determining a probability that the sensor has been previously used based upon results of the tests.

31. The system of claim 22 , wherein the first boundary comprises a first sensitivity value and the second boundary comprises a second sensitivity value.

32. The system of claim 22 , wherein the first boundary comprises a first baseline value and the second boundary comprises a second baseline value.

33. The system of claim 22 , wherein the first boundary delineates acceptable slopes and baselines of a conversion function and the second boundary delineates acceptable slopes and baselines of the conversion function.

34. The system of claim 22 , wherein the first and second set of time-dependent algorithmic functions comprise first and second parameters associated with a conversion function.

35. The system of claim 22 , wherein the first and second set of time-dependent algorithmic functions comprise first and second drift compensation functions.

36. The system of claim 35 , wherein the first and second drift compensation functions differ in the amount of drift compensation that they apply.

37. The system of claim 22 , wherein the first interval is predetermined prior to sensor insertion, and wherein a processor is configured to apply the second set of time-dependent algorithmic functions in response to elapsing of the predetermined first interval.

38. The system of claim 22 , wherein the first and second sets of time-dependent algorithmic functions comprise different conversion functions used to convert the sensor data into calibrated sensor data.

39. The system of claim 22 , wherein the first and second sets of time-dependent algorithmic functions comprise different parameters applied to a conversion function used to convert the sensor data into calibrated sensor data.

40. The system of claim 22 , wherein the first and second set of time-dependent algorithmic functions are determined prior to sensor implantation.

41. The system of claim 22 , wherein the processor is configured to apply the second set of time-dependent algorithmic functions to the sensor data associated with the second interval by dynamically applying a priori information based on time since sensor implantation.

42. The system of claim 22 , wherein the processor is configured to apply the second set of time-dependent algorithmic functions to the sensor data associated with the second interval by dynamically adapting a parameter of the second set of time-dependent algorithmic functions based on a prior knowledge of time-based sensor behavior during implantation.