Granted Patent
B2
US 9,724,320 · App. 14/767,767 · Granted Aug 8, 2017
Composition for preventing or treating renal fibrosis comprising dimethylfumarate as active ingredient
Inventors:
In Kyu Lee (Daegu, KR); Keun Gyu Park (Daegu, KR); Chang Joo Oh (Daegu, KR); Han Jong Kim (Daegu, KR); Joon-Young Kim (Daegu, KR)
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Abstract
The present invention relates to a composition for preventing or treating renal fibrosis comprising dimethylfumarate (DMF) as an active ingredient. The DMF according to the present invention has an excellent effect of reducing renal fibrosis by activating Nrf2 to inhibit TGF-β/Smad signaling, and thus is useful for preventing or treating renal fibrosis.
Claims (2)
1. A method of treating renal fibrosis, comprising administering to a patient in need thereof a composition comprising dimethylfumarate (DMF) as an active ingredient.
2. A method of improving renal fibrosis, comprising administering to a patient in need thereof a food composition comprising DMF as an active ingredient.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Dec 13, 2017
From: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY - ACADEMIC COOPERATION FOUNDATION; KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL
To: CURACLE CO., LTD.
Reel/Frame 044380/0320 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jul 20, 2017
From: LEE, IN KYU; PARK, KEUN GYU; OH, CHANG JOO; KIM, HAN JONG; KIM, JOON YOUNG
To: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY - ACADEMIC COOPERATION FOUNDATION; KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL
Reel/Frame 043275/0029 →
Priority Claims (1)
KR 10-2013-0015431
· Feb 13, 2013
· national
Continuity (1)