IP Library Granted Patent US 9,725,707
Granted Patent B2
US 9,725,707 · App. 14/431,549 · Granted Aug 8, 2017

3-epimerase

Inventors: Ryan David Woodyer (Hoffman Estates, IL); Richard W. Armentrout (Hoffman Estates, IL)
Assignee: TATE & LYLE INGREDIENTS AMERICAS LLC
C12N9/90C12P19/02C12P19/24C12Y501/03
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Quick Facts
Patent No.
US 9,725,707
App. No.
14/431,549
Granted
Aug 8, 2017
Kind
B2
Abstract

A protein comprising a polypeptide sequence having at least 70% sequence identity to SEQ ID NO:6, SEQ ID NO:2 or SEQ ID NO:4. The protein has ketose 3-epimerase activity.

Claims (15)

1. A protein comprising an amino acid sequence having 90% to 99% sequence identity to the amino acid sequence of SEQ ID NO: 6, wherein at least one amino acid within the amino acid sequence of the protein is substituted with a different amino acid at the corresponding position of the amino acid sequence of SEQ ID NO: 6, wherein the protein has allulose 3-epimerase activity, and wherein the amino acid sequence of the protein does not comprise the amino acid sequence of SEQ ID NO: 6.

2. The protein of claim 1 , wherein the protein is immobilized on a solid substrate.

3. The protein of claim 1 , wherein the protein comprises an amino acid sequence having 90% to 95% sequence identity to the amino acid sequence of SEQ ID NO: 6.

4. The protein of claim 3 , wherein the protein is immobilized on a solid substrate.

5. A nucleic acid molecule comprising a nucleotide sequence encoding the protein of claim 1 .

6. A vector comprising the nucleic acid molecule of claim 5 .

7. An isolated host cell comprising the nucleic acid molecule of claim 5 .

8. The isolated host cell of claim 7 , wherein the host cell is a microorganism, a mammalian cell, or a plant cell.

9. The isolated host cell of claim 8 , wherein the host cell is Escherichia coli.

10. A protein comprising the amino acid sequence of SEQ ID NO: 13, wherein the protein has allulose 3-epimerase activity.

11. A nucleic acid molecule comprising a nucleotide sequence encoding the protein of claim 3 .

12. A vector comprising t e nucleic acid molecule of claim 11 .

13. An isolated host cell comprising the nucleic acid molecule of claim 11 .

14. The isolated host cell of claim 13 , wherein the host cell is a microorganism, a mammalian cell, or a plant cell.

15. The isolated host cell of claim 14 , wherein the host cell is Escherichia coli.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 6, 2022
From: TATE & LYLE INGREDIENTS AMERICAS LLC
To: TATE & LYLE SOLUTIONS USA LLC
Reel/Frame 059516/0331 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 24, 2015
From: WOODYER, RYAN DAVID; ARMENTROUT, RICHARD W.
To: TATE & LYLE INGREDIENTS AMERICAS LLC
Reel/Frame 035489/0891 →
Priority Claims (1)
GB 1220554.8 · Nov 15, 2012 · national
Continuity (2)
Provisional Application 61706338 · Sep 27, 2012
Related Publication 20150210996A1 · Jul 30, 2015