IP Library Granted Patent US 9,750,580
Granted Patent B2
US 9,750,580 · App. 15/159,589 · Granted Sep 5, 2017

Method for enhancing ultrasound visibility of hyperechoic materials

Inventors: Frederick A. Ahari (Belleair Beach, FL); John S. Fisher (Belleair, FL)
Assignee: Devicor Medical Products, Inc.
A61B90/39A61F2/02A61K49/226A61L31/06A61L31/145A61B2090/3908A61B2090/3925A61B2090/3995
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Quick Facts
Patent No.
US 9,750,580
App. No.
15/159,589
Granted
Sep 5, 2017
Kind
B2
Abstract

A hydrogel plug is placed under stress during its curing stage, in one embodiment, by application of an externally applied force. The stress may also be induced during or after the dehydration process. The direction of the externally applied force increases the length, width, depth, or radial extent of the plug. The elastic limit of the plug is exceeded when the external force is applied so that the plug substantially retains its stressed size and shape when the externally applied force is removed. When the stretched or otherwise deformed dehydrated plug is hydrated, it substantially returns to the configuration it had prior to its dehydration and prior to the application of the externally applied force.

Claims (20)

1. A method for making a dehydrated hydrogel plug that expands in a controlled manner when hydrated, comprising the steps of:

preparing a dehydrated hydrogel plug and forming said dehydrated hydrogel plug so that it has a first predetermined geometric configuration when in a repose configuration;

subjecting said dehydrated hydrogel plug to a curing process;

inducing stress into said dehydrated hydrogel plug during said curing process;

controlling said stress so that said dehydrated hydrogel plug is stretched beyond its elastic limit and assumes a second preselected geometrical configuration when stretched beyond said elastic limit;

removing said externally applied force during the curing process so that the dehydrated hydrogel plug reaches said second predetermined geometrical configuration when the curing process is concluded;

whereby the dehydrated hydrogel plug, when hydrated, contracts until it assumes said in repose configuration, wherein the hydrogel plug exhibits a hypoechoic quality which improves the visibility of a hyperechoic marker, and said marker is at least partially imbedded in the hydrogel plug.

2. The method of claim 1 , further comprising the step of:

inducing said stress into said dehydrated hydrogel plug during said curing process by subjecting said dehydrated hydrogel plug to a force coincident with a longitudinal axis of said dehydrated hydrogel plug;

whereby said dehydrated hydrogel plug, when hydrated, contracts only in a longitudinal direction.

3. The method of claim 2 , further comprising the step of:

inducing said stress into said dehydrated hydrogel plug during said curing process by subjecting said dehydrated hydrogel plug to a force coincident with a transverse axis of said dehydrated hydrogel plug, said transverse axis being normal to said longitudinal axis;

whereby said dehydrated hydrogel plug, when hydrated, contracts only in a transverse direction.

4. The method of claim 3 , further comprising the step of:

inducing said stress into said dehydrated hydrogel plug during said curing process by subjecting said dehydrated hydrogel plug to a force coincident with an axis normal to said longitudinal axis and normal to said transverse axis of said dehydrated hydrogel plug;

whereby said dehydrated hydrogel plug, when hydrated, contracts only in a direction normal to said longitudinal axis and normal to said transverse axis.

5. The method of claim 4 , further comprising the step of:

inducing said stress into said dehydrated hydrogel plug during said curing process by subjecting said dehydrated hydrogel plug to a radial force, said radial force causing said dehydrated hydrogel plug to expand radially relative to a longitudinal axis and to contract along said longitudinal axis;

said dehydrated hydrogel plug, when hydrated, contracting in a radial direction relative to said longitudinal axis and lengthening along said longitudinal axis; and

determining a radial expansion to longitudinal contraction ratio by measuring the amount of radial expansion and the amount of longitudinal contraction during hydration and dividing the radial expansion by the longitudinal contraction.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 7, 2020
From: BIOPSY SCIENCES, LLC
To: MED-GENESIS, LLC
Reel/Frame 053998/0496 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 20, 2018
From: DEVICOR MEDICAL PRODUCTS, INC.
To: BIOPSY SCIENCES, LLC
Reel/Frame 045289/0549 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 29, 2016
From: MED-GENESIS, LLC
To: DEVICOR MEDICAL PRODUCTS, INC.
Reel/Frame 040806/0337 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 22, 2016
From: AHARI, FREDERICK; FISHER, JOHN S.
To: MED-GENESIS, LLC
Reel/Frame 039835/0814 →
Continuity (3)
Division 13911708 · Jun 6, 2013
Division 11277721 · Mar 28, 2006
Related Publication 20160262845A1 · Sep 15, 2016