IP Library Granted Patent US 9,828,337
Granted Patent B2
US 9,828,337 · App. 14/880,408 · Granted Nov 28, 2017

Lysine derivative having an isothiocyanate functional group and associated method of use

Inventor: Michael E. Silver (Holland, MI)
Assignee: The William M. Yarbrough Foundation
C07C331/20A61K9/0014A61K31/145A61K31/198A61K31/26A61K45/06A61K47/34
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Quick Facts
Patent No.
US 9,828,337
App. No.
14/880,408
Granted
Nov 28, 2017
Kind
B2
Abstract

A method for treating phytophotodermatitis including the steps of applying an isothiocyanate functional surfactant to an area affected by phytophotodermatitis, wherein said isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.

Claims (11)

1. A method for treating phytophotodermatitis with a lysine derivative surfactant having an isothiocyanate functional group, comprising the step(s) of:

applying a lysine derivative surfactant to an area affected by phytophotodermatitis, wherein the lysine derivative surfactant comprises an alkyl and/or alkanoyl substituent containing at least 8 carbon atoms bound to the α-nitrogen of the lysine, and further wherein the ε-nitrogen of the lysine forms part of an isothiocyanate functional group.

2. The method according to claim 1 , further comprising the step of applying an additional surfactant, wherein the additional surfactant is selected from at least one of the group comprising a non-ionic surfactant, an anionic surfactant, a cationic surfactant, a zwitterionic surfactant, and combinations thereof.

3. The method according to claim 1 , further comprising the step of applying an additional surfactant, wherein the additional surfactant comprises a non-ionic surfactant.

4. The method according to claim 1 , further comprising the step of applying an additional surfactant, wherein the additional surfactant comprises an anionic surfactant.

5. The method according to claim 1 , further comprising the step of applying an additional surfactant, wherein the additional surfactant comprises a cationic surfactant.

6. The method according to claim 1 , further comprising the step of applying an additional surfactant, wherein the additional surfactant comprises a zwitterionic surfactant.

7. A method for treating phytophotodermatitis with a lysine derivative surfactant having an isothiocyanate functional group, consisting essentially of the step of:

applying a lysine derivative surfactant to an area affected by phytophotodermatitis, wherein the lysine derivative surfactant comprises an alkyl and/or alkanoyl substituent containing at least 8 carbon atoms bound to the α-nitrogen of the lysine, and further wherein the ε-nitrogen of the lysine forms part of an isothiocyanate functional group.

8. A method for treating phytophotodermatitis with a lysine derivative surfactant having an isothiocyanate functional group, consisting of the step of:

applying a lysine derivative surfactant to an area affected by phytophotodermatitis, wherein the lysine derivative surfactant comprises an alkyl and/or alkanoyl substituent containing at least 8 carbon atoms bound to the α-nitrogen of the lysine, and further wherein the ε-nitrogen of the lysine forms part of an isothiocyanate functional group.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 3, 2017
From: SILVER, MICHAEL E.
To: THE WILLIAM M YARBROUGH FOUNDATION
Reel/Frame 041461/0001 →
Continuity (5)
Continuation 14594788 · Jan 12, 2015
Continuation 13342516 · Jan 3, 2012
Provisional Application 61429325 · Jan 3, 2011
Provisional Application 61502067 · Jun 28, 2011
Related Publication 20160030379A1 · Feb 4, 2016