IP Library Granted Patent US 9,933,607
Granted Patent B2
US 9,933,607 · App. 14/453,468 · Granted Apr 3, 2018

Microscope objective

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Quick Facts
Patent No.
US 9,933,607
App. No.
14/453,468
Granted
Apr 3, 2018
Kind
B2
Abstract

Provided here are microscope objectives that include a first plurality of lenses positioned within the passageway on a sample end of the microscope objective and a second plurality of lenses positioned within the passageway and spaced apart from the first plurality of lenses and opposite the sample end such that the first plurality of lenses and the second plurality of lenses are aligned along an imaging axis and such that each individual lens is rotationally symmetrical about the imaging axis. Also included is a motor configured to move a carrier along the imaging axis to change a distance between each lens of first plurality of lenses relative to at least one lens of the second plurality of lenses.

Claims (23)

1. An imaging system, comprising:

a microscope objective, comprising:

at least one closed-platform inaccessible objective turret;

a housing;

a sleeve forming a passageway in housing;

a first plurality of lenses positioned within the passageway on a sample end of the microscope objective;

a second plurality of lenses positioned within the passageway and spaced apart from the first plurality of lenses and opposite the sample end such that the first plurality of lenses and the second plurality of lenses are aligned along an imaging axis and such that each individual lens is rotationally symmetrical about the imaging axis;

a carrier coupled to the first plurality of lenses and positioned at least partially within the passageway;

an integral motor coupled to the carrier and configured to move the carrier along the imaging axis in conjunction with the at least one closed-platform inaccessible objective turret to change a distance between each lens of first plurality of lenses relative to at least one lens of the second plurality of lenses and thereby remotely adjust a spherical aberration (SA) setting of the microscope objective without direct user manipulation; and

a processor coupled to the motor and configured to provide instructions to drive the motor.

2. The imaging system of claim 1 , wherein the motor is configured to move the carrier to displace each lens of first plurality of lenses the same distance relative to a starting position such that each respective lens of the first plurality of lenses is fixed in position relative to one another.

3. The imaging system of claim 1 , wherein the housing is closed about the first plurality of lenses and the second plurality of lenses and the motor when the microscope objective is positioned within the imaging system.

4. The imaging system of claim 1 , wherein the housing is closed about the first plurality of lenses and the second plurality of lenses and the motor when the microscope objective is positioned within the imaging system.

5. The imaging system of claim 1 , wherein the carrier is positioned in part within the sleeve and in part extending from a sample end of the sleeve.

6. The imaging system of claim 1 , wherein the motor is positioned within a second passageway adjacent to the sleeve.

7. The imaging system of claim 6 , wherein an exterior wall of the sleeve forms a portion of an interior wall of the second passageway.

8. The imaging system of claim 6 , wherein the first passageway is larger than the second passageway.

9. The imaging system of claim 6 , wherein the housing forms a cylindrical shape conforming to the first passageway and a protrusion conforming to the second passageway.

10. The imaging system of claim 1 , wherein the first plurality of lenses comprises 3 or more lenses.

11. The imaging system of claim 10 , wherein the second plurality of lenses comprises 6 or more lenses.

12. The imaging system of claim 1 , wherein each lens of the second plurality of lenses is fixed in position within the passageway.

13. The imaging system of claim 1 , wherein the carrier is configured to move the first plurality of lenses away from the second plurality of lenses along the axis to increase the distance.

14. The imaging system of claim 1 , wherein the carrier is configured to move the first plurality of lenses towards the second plurality of lenses along the axis to decrease the distance.

Assignments (5)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2021
From: GLOBAL LIFE SCIENCES SOLUTIONS USA LLC
To: LEICA MICROSYSTEMS CMS GMBH
Reel/Frame 057261/0128 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 3, 2021
From: GLOBAL LIFE SCIENCES SOLUTIONS OPERATIONS UK LTD.
To: GLOBAL LIFE SCIENCES SOLUTIONS USA LLC
Reel/Frame 056113/0923 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 7, 2020
From: GE HEALTHCARE UK LIMITED
To: GLOBAL LIFE SCIENCES SOLUTIONS OPERATIONS UK LTD
Reel/Frame 054300/0369 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 5, 2020
From: GENERAL ELECTRIC COMPANY
To: GE HEALTHCARE UK LIMITED
Reel/Frame 053981/0329 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 6, 2014
From: MEYERS, MARK MARSHALL
To: GENERAL ELECTRIC COMPANY
Reel/Frame 033480/0781 →