Method for producing glyceric acid carbonate
View Patent ↗The present invention relates to a method for preparing a compound of the formula (I) with a specific definition of the substituent R 3 a mixture and also a corresponding application/use.
1. A method for preparing a compound of the formula (I)
where R 3 is selected from H and straight-chain, branched or cyclic C 1-12 -alkyl groups, the method comprising:
providing or preparing a compound of the formula (II)
where R 3 has the definition selected for formula (I), and
carrying out platinum-catalysed oxidation of the compound of the formula (II) with gaseous oxygen to give the compound of the formula (I).
2. The method according to claim 1 , wherein a catalyst is used for the platinum-catalysed oxidation comprising platinum as a solid, optionally comprising platinum as a solid on a support material, further optionally comprising platinum as a solid on carbon.
3. The method according to claim 1 , where R 3 is hydrogen.
4. The method according to claim 1 , wherein the platinum-catalysed oxidation is carried out in an aqueous medium.
5. The method according to claim 4 , wherein at the start of the platinum-catalysed oxidation in the aqueous medium the pH is 7 or <7.
6. The method according to claim 4 , wherein the platinum-catalysed oxidation is carried out such that, on formation of the compound of the formula (I), the pH in the aqueous medium decreases, optionally by at least 2 pH units.
7. The method according to claim 4 , wherein the platinum-catalysed oxidation is carried out without addition of base or buffer.
8. The method according to claim 4 , wherein the platinum-catalysed oxidation is carried out at least until the pH falls below 2, wherein at the start of the platinum-catalyzed oxidation in the aqueous medium the pH is 7 or less than 7.
9. The method according to claim 1 , wherein at the start of the platinum-catalysed oxidation the molar ratio of the platinum used to the compound of the formula (II) is greater than 2:100.
10. The method according to claim 1 , wherein the platinum-catalysed oxidation is carried out at least intermittently, optionally for most of the time, at a temperature in the range of 50 to 90° C.
11. The method according to claim 4 , wherein the platinum-catalysed oxidation is carried out in such a way that the gaseous oxygen is introduced into the aqueous medium.
12. A process comprising carrying out Heyns oxidation
(a) for oxidizing a compound of the formula (II)
where R 3 is selected from H and straight-chain, branched or cyclic C 1-12 -alkyl groups,
wherein the Heyns oxidation is carried out without addition of base or buffer.
13. A mixture comprising
a catalyst comprising platinum as a solid, optionally comprising platinum as a solid on a support material, further optionally comprising platinum as a solid on carbon,
and also
one or more compounds selected from the group consisting of
(a) compounds of the formula (II)
where R 3 is selected from H and straight-chain, branched or cyclic C 1-12 -alkyl groups,
and optionally one or more compounds selected from the group consisting of
(b) compounds of the formula (III)
where R 3 is selected from H and straight-chain, branched or cyclic C 1 - 12 -alkyl groups.