IP Library Granted Patent US 7,138,148
Granted Patent B2
US 7,138,148 · App. 10/481,953 · Granted Nov 21, 2006

Use of extracts of

Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (SCRAS)
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Quick Facts
Patent No.
US 7,138,148
App. No.
10/481,953
Granted
Nov 21, 2006
Kind
B2
Abstract

The invention concerns the use of Ginkgo biloba extracts, and in particular Ginkgo biloba extracts comprising 20 to 30% of flavoneglycosides, 2.5 to 4.5% in total of gingkolides A, B, C and J, 2 to 4% of bilobalide, less than 10% of proanthocyanidins and at least 10 ppm of alkylphenol type compounds, for preparing a medicine for treating sarcopenia.

Claims (11)

1. A method of treating sarcopenia in warm-blooded animals comprising administering to warm-blooded animals in need thereof an amount of an extract of Ginkgo biloba comprising from 20 to 30% of flavoneglycosides, from 2.5 to 4.5% in total of ginkgolides A, B, C and J, from 2 to 4% of bilobalide, less than 10% of proanthocyanidines and less than 10 ppm of compounds of alkylphenol type sufficient to treat sarcopenia.

2. The method of claim 1 wherein the extract of Ginkgo biloba comprises less than 5 ppm of compounds of alkylphenol type.

3. The method of claim 1 wherein the extract of Ginkgo biloba comprises a compound of the formula

wherein W, X, Y and Z are independently selected from the group consisting of H, —OH, alkoxy and —O-G S , G S -OH being a mono- or a disaccharide, it being understood that at least one of W, X, Y or Z is —O-G S .

4. The method of claim 3 , wherein the compounds of formula (I) are such that X is OH or O-G S , O-G S -OH is a mono- or a disaccharide, and:

either W is OH or O-G S , Y is H and Z is H;

or W is OH or O-G S , Y is OH or O-G S ; and Z is H;

or W is OH or O-G S , Y is OH or O-G S and Z is OH or O-G S ;

or W is OH or O-G S , Y is H and Z is OH or O-G S ;

or W is H, Y is OH or O-G S and Z is OH or O-G S ;

or W is OH or O-G S , Y is alkoxy and Z is H.

Assignments (2)
CHANGE OF NAME Recorded Feb 11, 2009
From: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES
To: IPSEN PHARMA S.A.S.
Reel/Frame 022240/0147 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 22, 2003
From: CHRISTEN, YVES
To: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUE (S.C.R.A.S.)
Reel/Frame 015276/0433 →
Priority Claims (1)
FR 01 09506 · Jul 17, 2001 · national
Continuity (1)
Related Publication 20040166180A1 · Aug 26, 2004