Method and device for assisting in a tissue treatment
View Patent ↗A method for planning to treat tissue by administering a substance which emits energy or can interact with administered energy to a body, such as body tissue, wherein a dispersion of the substance in the body is simulated, and to a system or device for planning administering a substance and administering energy to a body or in body tissue. The device includes a data capture unit configured to detect patient-specific parameters, wherein the patient-specific parameters can be used to describe a dispersion behavior of the substance in the body or body tissue; a computational unit operatively coupled to the data capture unit, said computational unit configured to obtain the patient-specific parameters from the data capture unit; a database accessible by the computational unit, wherein the database includes data for describing characteristics of a particular type of tissue or a particular body structure, data for describing mechanisms for supplying energy, and/or data for describing the effect on tissue of a substance in combination with supplied energy, the computational unit being configured to retrieve and/or store said data in the database; and an input unit via which a user can input treatment-specific data to the computational unit, wherein the computational unit is configured to simulate the plan based on at least one of the patient-specific data, data stored in the database, or user input data.
1. A method for planning to treat tissue by administering a substance to a body or body tissue, comprising:
using a processor to simulate a dispersion of the substance in the body or body tissue, said dispersion corresponding to movement of the substance through the body or body tissue, wherein said substance comprises a substance that emits energy or interacts with administered energy;
simulating a therapeutic effect that supplying at least one of external radiation energy, heat energy, cooling energy or light energy has on at least one of the administered substance, the body or body tissue, wherein simulating the therapeutic effect takes into account the simulated dispersion of the substance in the body or body tissue; and
iteratively performing the simulation when a result of the simulation indicates the effect on the body or body tissue is below a predetermined minimum effect.
2. The method as set forth in claim 1 , further comprising simulating the interaction of the substance with the body or body tissue.
3. The method as set forth in claim 1 , further comprising ascertaining and using in the simulation body or body tissue characteristics of one or more types of body tissue.
4. The method of claim 3 , wherein ascertaining and using body or body tissue characteristics includes physical, chemical or physiological parameters of the body or body tissue.
5. The method according to claim 1 , further comprising:
simulating at least one of an effect that the body or body tissue, the administration of the substance, or the delivered energy has on the substance.
6. The method as set forth in claim 1 , further comprising transferring one or more parameters used in the simulation to a navigation system, wherein said parameters describe at least one of administration of the substance or administration of energy, and wherein the navigation system executes the treatment when a result of the simulation achieves a predetermined result.
7. The method as set forth in claim 1 , further comprising:
examining an effect of at least one of administering the substance or administering the energy; and
re-planning the treatment if actual treatment deviates from the simulated treatment.
8. The method as set forth in claim 1 , further comprising using a radioactive liquid as an agent for brachytherapy.
9. A computer program embodied on a non-transitory computer readable storage medium, wherein the program instructs a processor to perform the method as set forth in claim 1 .
10. The method according to claim 1 , wherein the substance is a substance that emits energy, further comprising calculating a distribution of the energy emitted by the substance.
11. The method according to claim 1 , wherein the substance is a sensitizer.
12. The method according to claim 1 , further comprising:
determining anatomical or physiological information concerning the body or body tissue;
determining characteristics of the substance;
determining energy supply parameters; and
using the determined anatomical or physiological information, characteristics of the substance, and energy supply parameters to perform the simulation.
13. The method according to claim 1 , further comprising:
based on the simulated dispersion of the substance in the body or body tissue, simulating a distribution of energy supplied by the substance or by an energy source to the body or body tissue; and
simulating an effect of administering the substance and supplying the energy has on the body or body tissue.