METHOD OF INCREASING THE EFFECTIVENESS OF A CONTACT LENS CLEANING SOLUTION AGAINST RESISTANT STRAIN FUNGI
A method of making a disinfecting solution that is effective at disinfecting contact lenses. The method includes the step of combining water, one or more antimicrobial agents and a reduced amount of solid content into a dissolved liquid mixture. The process results in an improved disinfection efficacy compared to a reference solution.
1 . In a method of manufacturing a disinfecting solution for disinfecting a contact lens inoculated with resistant strain fusarium microbes by contacting the contact lens with a disinfecting solution comprising water, an antimicrobial agent and a surfactant, a wetting agent, viscosity enhancing agent, a pH adjusting agent and a tonicity adjusting agent, the improvement comprising lowering the surfactant concentration of the disinfecting solution compared to a reference solution.
2 . The method of claim 1 , wherein the surfactant is a non-ionic surfactant.
3 . The method of claim 1 , wherein the amount of surfactant is reduced by 25 percent of the amount of surfactant in the reference solution.
4 . The method of claim 1 , further comprising increasing the tonicity of the solution.
5 . The method of claim 1 , wherein the solution has enhanced efficacy against resistant strain fusarium microbes.
6 . The method of claim 1 , further comprising adding a protein removal agent.
7 . The method of claim 1 , wherein the antimicrobial agent is a quaternary ammonium or biguamide antimicrobial agent.
8 . The method of claim 1 , wherein the surfactant is a poly(ethylene oxide)/poly(propylene oxide) containing surfactant
9 . A method of making a disinfecting solution that is effective at disinfecting a contact lens comprising water, an antimicrobial agent and one or more surfactants, the method comprising the step of combining the water, antimicrobial agent and a reduced amount of solid content into a dissolved liquid mixture, wherein the disinfecting solution has enhanced efficacy against resistant strain fusarium microbes compared to solutions without a reduced amount of solid content.
10 . The method of claim 9 , wherein the surfactant is a non-ionic surfactant.
11 . The method of claim 9 , wherein the amount of surfactant is reduced by 25 percent of the amount of surfactant in the reference solution.
12 . The method of claim 9 , further comprising increasing the tonicity of the solution.
13 . The method of claim 9 , wherein the solution has enhanced efficacy against resistant strain fusarium microbes.
14 . The method of claim 9 , further comprising adding a protein removal agent.
15 . The method of claim 9 , wherein the antimicrobial agent is a quaternary ammonium or biguamide antimicrobial agent.
16 . The method of claim 9 , wherein the surfactant is a poly(ethylene oxide)/poly(propylene oxide) containing surfactant.
17 . The method of claim 9 , wherein the surfactant is a poloxamer surfactant.