Pharmaceutical Formulation
This invention relates to a stable pharmaceutical formulation containing olanzapine. The composition comprises olanzapine or a pharmaceutically acceptable salt thereof, one or more suitable pharmaceutical excipients and a compound of formula (I) and/or a compound of formula (II): or a pharmaceutically acceptable salt thereof.
1 . A pharmaceutical composition comprising olanzapine or a pharmaceutically acceptable salt thereof, one or more suitable pharmaceutical excipients and a compound of formula I and/or a compound of formula II:
or a pharmaceutically acceptable salt thereof.
2 . A pharmaceutical composition according to claim 1 , wherein the compound of formula I or a pharmaceutically acceptable salt thereof is present at 0.001 to 5 wt % based on the weight of olanzapine or the pharmaceutically acceptable salt thereof.
3 . A pharmaceutical composition according to claim 1 , wherein the compound of formula II or a pharmaceutically acceptable salt thereof is present at 0.001 to 5 wt % based on the weight of olanzapine or the pharmaceutically acceptable salt thereof.
4 . A pharmaceutical composition according to claim 1 , wherein the compound of formula I and the compound of formula II or a pharmaceutically acceptable salt thereof are both present at a total of 0.001 to 5 wt % based on the weight of olanzapine or the pharmaceutically acceptable salt thereof.
5 . A pharmaceutical composition comprising the compound of formula I or a pharmaceutically acceptable salt thereof and/or formula II or a pharmaceutically acceptable salt thereof, and one or more suitable pharmaceutical excipients.
6 . (canceled)
7 . (canceled)