Identifier circuits for generating unique identifiable indicators and techniques for producing same
View Patent ↗The present invention provides for safe and reliable electronic circuitry that can be employed in ingestible compositions. The ingestible circuitry of the invention includes a solid support; a conductive element; and an electronic component. Each of the support, conductive element and electronic component are fabricated from an ingestible material. The ingestible circuitry finds use in a variety of different applications, including as components of ingestible identifiers, such as may be found in ingestible event markers, e.g., pharma-informatics enabled pharmaceutical compositions.
1. A method of producing an identifier, the method comprising:
laminating a non-conducting element between first and second dissimilar materials to create a laminate component, wherein the first and second dissimilar materials generate a voltage potential when in contact with a conducting fluid;
removing a portion of the first and second dissimilar materials from the perimeter of the laminate component to expose the non-conducting element and to create a skirt; and
securing a circuit within an aperture formed in the laminate component, wherein the circuit is electrically coupled to each of the first and second dissimilar materials, and wherein the circuit is operable by the voltage potential generated by the first and second dissimilar materials.
2. The method of claim 1 , further comprising selecting the first and second dissimilar materials to create a voltaic cell through oxidation and reduction reactions when the first and second dissimilar materials are in contact with the conducting fluid.
3. The method of claim 2 , further comprising configuring the circuit to generate a detectable signal that identifies unique information associated with the identifier.
4. The method of claim 2 , wherein the conducting fluid is a physiological fluid.
5. The method of claim 1 , further comprising securing the identifier to a pharmaceutical product to produce a tagged product such that activation of the circuit is an indication that the pharmaceutical product of the tagged product is in contact with physiological fluid.
6. The method of claim 5 , further comprising sealing the tagged product with a coating to isolate the tagged product from the physiological fluid for a predefined period of time until the coating is dissolved by the physiological fluid to allow the tagged product to reach a target site at which time the tagged product is exposed to the physiological fluid.
7. The method of claim 1 , further comprising laminating a current collector element between the non-conducting element and at least one of the first and second dissimilar materials.
8. The method of claim 1 , further comprising forming the aperture through the laminate component to receive the circuit within the aperture.
9. The method of claim 1 , further comprising fixing the circuit within the aperture with a conductive adhesive.
10. The method of claim 1 , further comprising removing a portion of the laminate component encompassing the circuit to produce the identifier.