IP Library Granted Patent US 8,055,334
Granted Patent B2
US 8,055,334 · App. 12/665,022 · Granted Nov 8, 2011

Evaluation of gastrointestinal function using portable electroviscerography systems and methods of using the same

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Quick Facts
Patent No.
US 8,055,334
App. No.
12/665,022
Granted
Nov 8, 2011
Kind
B2
Abstract

Portable electroviscerography systems are provided. Aspects of the systems include a body-associated receiver and an ingestible identifier unit, both of which are configured to detect visceral electrical signals. The system communicates with an extra-corporeal data processor configured to receive data from the body-associated receiver and generate and electroviscerogram from the received data. Also provided are methods of producing electroviscerograms using systems of the present invention.

Claims (20)

1. A system for detection of myoelectric activity, the system comprising:

a receiver unit capable of detecting voltage potential changes, wherein the receiver unit comprises a transmission module for sending encoded information to a remote location and at least one sensor electrode to gather information from a proximal environment;

an ingestible identifier in communication with the receiver unit, wherein the identifier comprises:

a housing including a first electrode and a second electrode secured thereto;

a control unit electrically coupled to the first and second electrodes, wherein the control unit changes the conductance between the first and second electrodes; and

a detection unit electrically coupled to the first and second electrodes, wherein the detection unit reads a surrounding environment to collect information,

wherein electrochemical reactions between the first electrode and the surrounding environment and the second electrode and the surrounding environment respectively produce a voltage potential that powers the ingestible identifier such that the control unit switches the ingestible identifier between broadcast mode and detection mode; and

a second ingestible identifier wherein the second ingestible identifier communicates with the ingestible identifier such that when the second ingestible identifier is in broadcast mode, the ingestible identifier is in detection mode thereby allowing the ingestible identifiers to communicate.

2. The system of claim 1 , further comprising a second receiver unit that includes at least three electrodes and wherein each of the electrodes of the second receiver unit transmits a control signal that is detected by each of the ingestible identifiers to create a detection array within the subject wherein the location of each ingestible identifier can be determined.

3. The system of claim 1 , wherein the ingestible identifier measures acidic conditions and the second ingestible identifier measures alkaline conditions.

4. The system of claim 1 , wherein the system further comprises an extra-corporeal data processor configured to receive data from the receiver unit and generate an electroviscerogram from the received data.

5. The system of claim 1 , wherein the ingestible identifier includes a disc secured to the housing, wherein the disk is non-conducting and wherein during the detection mode the ingestible identifier records data associated with myoelectric activity and during the broadcast phase the ingestible identifier produces a unique current signature including the data.

6. The system of claim 1 , wherein during the detection mode the ingestible identifier detects and records data associated an implantable device and during the broadcast phase the ingestible identifier produces a unique current signature encoded with the data.

7. The system of claim 1 , wherein the information encoded in the unique current signature produced by the ingestible identifier is identification information to indicate activation of the ingestible identifier to the receiver.

8. The system of claim 1 , wherein the information encoded in the ingestible identifier's unique current signature represents the data gathered during the detection stage.

9. The system of claim 1 , wherein the receiver unit further comprises a second sensor electrode positioned apart from the at least one sensor electrode.

10. The system of claim 9 , wherein the receiver further comprises a detection module capable of detecting low frequency current signals produced by a voltage potential and capable of detecting high frequency current signals produced by the ingestible identifier.

11. The system of claim 1 , wherein the ingestible identifier further comprises a temperature sensing unit responsive to and capable of recording the surrounding temperature.

12. The system of claim 1 , wherein the ingestible identifier includes a sensor capable of measuring the surrounding temperature.

13. The system of claim 1 , wherein the ingestible identifier includes a sensor capable of measuring the surrounding pH level.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 18, 2024
From: PROTEUS DIGITAL HEALTH INC.,
To: OTSUKA AMERICA PHARMACEUTICAL, INC.
Reel/Frame 068980/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 18, 2024
From: OTSUKA AMERICA PHARMACEUTICAL, INC.
To: OTSUKA PHARMACEUTICAL CO., LTD.
Reel/Frame 068980/0277 →
CHANGE OF NAME Recorded Nov 2, 2012
From: PROTEUS BIOMEDICAL, INC.
To: PROTEUS DIGITAL HEALTH, INC.
Reel/Frame 029228/0436 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 18, 2009
From: SAVAGE, GEORGE; HAFEZI, HOOMAN; COLLIOU, OLIVIER; ZDEBLICK, MARK; STRAND, ANGELA
To: PROTEUS BIOMEDICAL, INC.
Reel/Frame 023680/0083 →