Methicillin-resistant
View Patent ↗This present provides kaempferol-3-(2-E,3-Z-di-p-coumaroyl)-rhamnoside, kaempferol-3-(2-Z-3-E-di-p-coumaroyl)-rhamnoside, and kaempferol-3-(2,3-di-Z-p-coumaroyl)-rhamnoside compounds useful as a new class of anti-bacterial agents. These compounds are extracted from Platanus occidentalis . These compounds were found to exhibit anti-bacterial activity against methicillin resistant Staphylococcus aureus (MRSA).
1. A composition comprising a mixture of kaempferol3-0-α-L-(2″,3″-di-E-p-coumaroyl)-rhamnoside; kaempferol 3-0-α-L-(2″-E-p-coumaroyl-3″-Z-p-coumaroyl)-rhamnoside; kaempferol 3-0-α-L-(2″-Z-p-coumaroyl-3″-E-p-coumaroyl)-rhamnoside; and kaempferol 3-0-α-L-(2″,3″-di-Z-p-coumaroyl)-rhamnoside.
2. A topical or surface disinfectant comprising at least one compound or mixtures of compounds of claim 1 alone or in combination with an additional herbal or disinfectant.
3. The antiseptic of claim 2 for use on a mammal.
4. A compound comprised of a formula
Z-p-coumaroyl
R 1 ═R 2 =Z-p-coumaroyl.
5. A topical or surface disinfectant comprising the compound of claim 4 alone or in combination with an additional herbal or disinfectant.
6. The disinfectant of claim 5 for use on a mammal.