IP Library Granted Patent US 8,738,154
Granted Patent B2
US 8,738,154 · App. 13/115,031 · Granted May 27, 2014

Multiplexed multi-electrode neurostimulation devices

Inventors: Mark Zdeblick (Portola Valley, CA); Todd Thompson (San Jose, CA); Marc Jensen (Los Gatos, CA); Olivier Colliou (Los Gatos, CA); Angela Strand (Portland, OR)
Assignee: Proteus Digital Health, Inc.
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Quick Facts
Patent No.
US 8,738,154
App. No.
13/115,031
Granted
May 27, 2014
Kind
B2
Abstract

Implantable stimulation devices are provided. Aspects of the devices include a multiplexed multi-electrode component configured for neural stimulation. The multiplexed multi-electrode component includes two or more individually addressable satellite electrode structures electrically coupled to a common conductor. The satellite structures include a hermetically sealed integrated circuit controller operatively coupled to one or more electrodes. Also provided are systems that include the devices of the invention, as well as methods of using the systems and devices in a variety of different applications.

Claims (23)

1. An implantable device for target site stimulation, the device comprising:

a multiplexed lead comprising at least one conductor;

a plurality of multiplexed addressable units secured at predetermined locations along the conductor, wherein each addressable unit comprises:

a multi-port connector defining a plurality of ports, wherein each port receives an electrode lead that is electrically coupled to and secured to the multi-port connector and each electrode lead includes a plurality of independently excitable electrodes; and

a plurality of independently addressable integrated circuits corresponding to the number of defined ports in the multi-port connector, wherein each circuit is electrically coupled to the corresponding electrode lead at the corresponding port and wherein each circuit controls the power flowing to each of the plurality of independently excitable electrodes of the respective electrode lead in the corresponding port; and

a hermetically sealed control unit electrically coupled to one end of the conductor distal from the addressable units, wherein the control unit provides control information and power to each of the plurality of multiplexed addressable units through the conductor, wherein the multiplexed addressable units are arranged and multiplexed in a linear configuration.

2. The implantable device of claim 1 wherein at least one electrode lead comprises four independently excitable electrodes.

3. The implantable device of claim 2 wherein the four independently excitable electrodes are uniformly and axially positioned about the respective electrode lead.

4. The implantable device of claim 3 wherein at least one other electrode lead comprises six independently excitable electrodes.

5. The implantable device of claim 4 wherein the six independently excitable electrodes are uniformly and axially positioned about the respective electrode lead.

6. The implantable device of claim 1 wherein the multiplexed lead further comprises a second conductor electrically coupled to the control unit at one end and electrically coupled to the addressable units along at least a portion of its length.

7. The implantable device of claim 1 wherein the plurality of independently excitable electrodes of at least one electrode are positioned radially about the respective electrode lead.

8. The implantable device of claim 1 wherein the target site is a spinal nerve and wherein the device is shaped to at least partially surround the spinal nerve and wherein the multiplexed lead further comprises a second conductor secured and electrically coupled to at least a portion of the plurality of addressable units.

9. The implantable device of claim 8 wherein the plurality of independently excitable electrodes of at least one electrode lead are positioned on one side of the respective electrode lead.

10. The implantable device of claim 9 wherein the plurality of independently excitable electrodes of at least one other electrode lead are staggered along the respective electrode lead.

11. The implantable device of claim 1 further comprising:

a target lead electrically coupled to the control unit, wherein the target lead comprises:

a conducting wire continuing along at least a portion of the length of the target lead;

a hermetically sealed addressable target controller electrically coupled to the conducting wire and positioned at one end of the target lead;

a plurality of addressable target units including a plurality of electrodes wherein each target unit is electrically coupled to the conducing wire through the target controller,

wherein the control unit transmits programming information to the target controller of the target lead.

12. The implantable device of claim 10 further comprising a power storage unit coupled to the conductor of the lead for supplying power to the electrode structures through the integrated circuit controller.

13. The implantable device of claim 10 wherein the plurality of independently addressable integrated circuits are hermetically sealed.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 18, 2024
From: PROTEUS DIGITAL HEALTH INC.,
To: OTSUKA AMERICA PHARMACEUTICAL, INC.
Reel/Frame 068980/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 18, 2024
From: OTSUKA AMERICA PHARMACEUTICAL, INC.
To: OTSUKA PHARMACEUTICAL CO., LTD.
Reel/Frame 068980/0277 →
CHANGE OF NAME Recorded Nov 2, 2012
From: PROTEUS BIOMEDICAL, INC.
To: PROTEUS DIGITAL HEALTH, INC.
Reel/Frame 029228/0436 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 31, 2011
From: ZDEBLICK, MARK; THOMPSON, TODD; JENSEN, MARC; COLLIOU, OLIVIER; STRAND, ANGELA
To: PROTEUS BIOMEDICAL, INC.
Reel/Frame 026365/0114 →
Continuity (3)
Continuation 12665030
Provisional Application 61114433 · Nov 13, 2008
Related Publication 20110224757A1 · Sep 15, 2011