Multi-mode communication ingestible event markers and systems, and methods of using the same
View Patent ↗Aspects of the invention include multi-mode communication ingestible event marker devices. Ingestible event marker devices of the invention include an ingestible component comprising a conductive communication module and at least one additional non-conductive communication module. The non-conductive communication module may be integrated with the ingestible component or at least a portion or all of the non-conductive communication module may be associated with a packaging component of the ingestible event marker device. Additional aspects of the invention include systems that include the devices and one or more receivers, as well as methods of using the same.
1. A method, comprising:
detecting at least one of a first signal and a second signal from a device comprising:
an ingestible component comprising an integrated circuit comprising a conductive communication module configured to emit the first signal, wherein the first signal generated by the conductive communication module is a near field signal that is communicated via a conductive communication protocol that uses fluid as a conduction medium; and
at least a portion of a non-conductive communication module configured to emit the second signal.
2. The method of claim 1 , wherein the method includes detecting the first signal.
3. The method of claim 1 , wherein the method includes detecting the second signal.
4. The method of claim 1 , wherein the method includes detecting the first signal and the second signal.
5. A method comprising:
emitting at least one of a first signal or a second signal from a device comprising:
an ingestible component comprising an integrated circuit comprising a conductive communication module configured to emit the first signal, wherein the first signal generated by the conductive communication module is a near field signal that is communicated via a conductive communication protocol that uses fluid as a conduction medium; and
at least a portion of a non-conductive communication module configured to emit the second signal.
6. The method of claim 5 , wherein the method includes emitting the first signal.
7. The method of claim 5 , wherein the method includes emitting the second signal.
8. The method of claim 5 , wherein the method includes emitting the first signal and the second signal.
9. A method, comprising:
transmitting a signal between a non-conductive communication module and a receiver, wherein the non-conductive communication module is a component of a device comprising:
an ingestible component comprising an integrated circuit comprising a conductive communication module, wherein the conductive communication module generates a near field signal that is communicated via a conductive communication protocol that uses fluid as a conduction medium; and
the non-conductive communication module.
10. The method of claim 9 , wherein the receiver is a component chosen from a system selected from the group consisting of manufacturing systems, supply chain management systems and health care management systems.
11. The method of claim 10 , wherein the receiver is a component of a manufacturing system.
12. The method of claim 11 , wherein the manufacturing system is a high-throughput manufacturing system.
13. The method of claim 11 , wherein the signal is transmitted from the device to the receiver.
14. The method of claim 11 , wherein the signal is transmitted from the receiver to the device.
15. The method of claim 10 , wherein the receiver is a component of a supply chain management system.
16. The method of claim 15 , wherein the signal is transmitted from the device to the receiver.
17. The method of claim 15 , wherein the signal is transmitted from the receiver to the device.
18. The method of claim 10 , wherein the receiver is a component of a health care management system.
19. The method of claim 18 , wherein the signal is transmitted from the device to the receiver.
20. The method of claim 18 , wherein the signal is transmitted from the receiver to the device.
21. A method comprising:
administering to a subject a device comprising:
an ingestible component comprising an integrated circuit comprising a conductive communication module configured to emit the first signal, wherein the first signal generated by the conductive communication module is a near field signal that is communicated via a conductive communication protocol that uses fluid as a conduction medium; and
at least a portion of a non-conductive communication module configured to emit the second signal.
22. The method of claim 21 , wherein the method further comprises receiving the first signal at a receiver.
23. The method of claim 22 , wherein the method further comprises determining historical information for the ingestible component from the received first signal.
24. The method of claim 21 , wherein the ingestible component includes an active pharmaceutical agent.
25. The method of claim 24 , wherein the ingestible component comprises a physiologically acceptable vehicle.
26. The method of claim 25 , wherein the physiologically acceptable vehicle is configured as a tablet or capsule.