Perfusion assessment multi-modality optical medical device
A perfusion assessment multi-modality optical medical device comprising ⋅ a white light image sensor ( 320 ) and optical system configured to image a body area of interest ( 130, 340 ), a coherent light source ( 330 ) for illuminating said body area of interest with wavelength of 760-810 nm, an optical coherence imaging (OCI) image sensor ( 310 ) detecting the fluctuations of the backscattered light ( 302 ) near the illumination wavelength from at least part of said illuminated body area of interest ( 340 ), a fluorescence image sensor ( 315 ) to detect the fluorescence signal at higher wavelength than the illumination wavelength from at least part of said illuminated body area of interest ( 340 ), a screen ( 115, 210 ) to show the results from the modalities, all previous items being included in a single movable unit ( 200 ) which furthermore comprises a processing unit ( 105, 110 ) to calculate perfusion map from the OCI image sensor ( 310 ) using LDI or LSI algorithms, wherein said white light image sensor ( 320 ), said OCI image sensor ( 310 ) and said fluorescence image sensor ( 315 ), at least partially, use a common optical path ( 610 ).
1. A perfusion assessment multi-modality optical medical device comprising:
a coherent light source for illuminating a body area of interest;
an optical coherent imaging (OCI) image sensor that detects fluctuations of backscattered light near the illumination wavelength from at least part of said illuminated body area of interest;
a fluorescence image sensor to detect a fluorescence signal at a wavelength different from the illumination wavelength from at least part of said illuminated body area interest;
a screen, the coherent light source, the OCI image sensor, the fluorescence image sensor, and the screen are included in a single movable unit, said OCI image sensor, and said fluorescence image sensor, at least partially, use a common optical path; and
a processing unit coupled to the OCI image sensor and the fluorescence image sensor for comparing the blood flow or perfusion information in the OCI image and in the fluorescence image to differentiate microcirculatory blood perfusion from larger vessels with the blood flow being faster in the larger vessels and wherein the results of the comparison are displayed on the screen.
2. The device according to claim 1 , wherein said OCI image sensor and said fluorescence image sensor are a single image sensor.
3. The device according to claim 1 , further including a white light image sensor and an optical system configured to image the body area of interest and wherein the white light image sensor is configured such that a body area of interest can be shown with at least 1.5×magnification.
4. The device according to claim 1 , further comprising detecting means for the position and orientation of the device head in relation to a patient.
5. The device according to claim 4 , wherein the processing unit renders stored images and/or metadata related to the currently visualized body area.
6. The device according to claim 1 , wherein the processing unit is used to generate an overlay image from the OCI image information and fluorescence image information.
7. The device according to claim 3 , further comprising an auto-focus system for the white light image wherein the focus point is automatically detected by locating the point on the screen which is focused by the user's eye.
8. The device according to claim 1 wherein coherent light source generates a wavelength of 760-810 nm.
9. A perfusion assessment multi-modality optical medical device comprising:
a coherent light source for illuminating a body area of interest;
an optical coherent imaging (OCI) image sensor that detects fluctuations of backscattered light near the illumination wavelength from at least part of said illuminated body area of interest;
a fluorescence image sensor to detect a fluorescence signal at a wavelength different from the illumination wavelength from at least part of said illuminated body area interest, said OCI image sensor, and said fluorescence image sensor, at least partially, use a common optical path;
a screen; and
a processing unit coupled to the OCI image sensor and the fluorescence image sensor for comparing the blood flow information in the OCI image and in the fluorescence image to differentiate the contribution of blood flow in different depths within the body area and wherein the results of the comparison are displayed on the screen.
10. The device according to claim 9 , wherein said OCI image sensor and said fluorescence image sensor are a single image sensor.
11. The device according to claim 9 , further including a white light image sensor and an optical system configured to image the body area of interest.
12. The device according to claim 9 wherein coherent light source generates a wavelength of 760-810 nm.
13. A perfusion assessment multi-modality optical medical device comprising:
a coherent light source for illuminating a body area of interest;
an optical coherent imaging (OCI) image sensor that detects fluctuations of backscattered light near the illumination wavelength from at least part of said illuminated body area of interest;
a fluorescence image sensor to detect a fluorescence signal at wavelength different from the illumination wavelength from at least part of said illuminated body area interest, said OCI image sensor, and said fluorescence image sensor, at least partially, use a common optical path;
a screen; and
a processing unit coupled to the OCI image sensor and the fluorescence image sensor for comparing the blood flow or perfusion information in the OCI image and in the fluorescence image to determine the reliability of the measurements, wherein when the results of the comparison are similar, the measurements are considered more reliable than when the results are different and for generating and displaying on the screen a reliability map.
14. The device according to claim 13 , wherein said OCI image sensor and said fluorescence image sensor are a single image sensor.
15. The device according to claim 13 , further including a white light image sensor and an optical system configured to image the body area of interest.
16. The device according to claim 1 wherein coherent light source generates a wavelength of 760-810 nm.