IP Library Granted Patent US 9,586,937
Granted Patent B2
US 9,586,937 · App. 15/215,628 · Granted Mar 7, 2017

sGC stimulators

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Quick Facts
Patent No.
US 9,586,937
App. No.
15/215,628
Granted
Mar 7, 2017
Kind
B2
Abstract

Compounds of Formulae I′ and I are described, which are useful as stimulators of sGC, particularly NO-independent, heme-dependent stimulators. These compounds are also useful for treating, preventing or managing various disorders that are herein disclosed.

Claims (3)

1. A compound of formula:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and one or more excipients.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 10, 2019
From: IRONWOOD PHARMACEUTICALS, INC.
To: CYCLERION THERAPEUTICS, INC.
Reel/Frame 048853/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 4, 2016
From: NAKAI, TAKASHI; MOORE, JOEL; PERL, NICHOLAS ROBERT; IYENGAR, RAJESH R.; MERMERIAN, ARA; IM, G-YOON JAMIE; LEE, THOMAS WAI-HO; HUDSON, COLLEEN; RENNIE, GLEN ROBERT; JIA, JAMES; RENHOWE, PAUL ALLAN; JUNG, JOON; BARDEN, TIMOTHY CLAUDE; YU, XIANG Y.; SHEPPECK, JAMES EDWARD, II; IYER, KARTHIK; MILNE, GEORGE TODD; LONG, KIMBERLY KAFADAR; CURRIE, MARK G.
To: IRONWOOD PHARMACEUTICALS, INC.
Reel/Frame 040224/0680 →