IP Library › Granted Patent US 10,526,388
Granted Patent B2
US 10,526,388 · App. 15/556,694 · Granted Jan 7, 2020

Peptide derived from GPC3, pharmaceutical composition for treatment or prevention of cancer using the same, immunity inducer, and method for producing antigen-presenting cells

Inventors: Tomoya Miyakawa (Tokyo, JP); Masaaki Oka (Yamaguchi, JP); Shoichi Hazama (Yamaguchi, JP); Koji Tamada (Yamaguchi, JP); Keiko Udaka (Kochi, JP)
Assignee: Cytlimic Inc.
C07K14/4748A61K38/00A61K38/1764A61K39/00A61K39/0011A61P35/00A61P37/04C07K14/705A61K2039/572
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Quick Facts
Patent No.
US 10,526,388
App. No.
15/556,694
Granted
Jan 7, 2020
Kind
B2
Abstract

The present invention provides a peptide containing 8 or more consecutive amino acid residues in an amino acid sequence of any of SEQ ID NOS: 1 to 11 and consisting of 11 or less amino acid residues.

Claims (9)

1. A peptide comprising 8 or more consecutive amino acid residues in an amino acid sequence of SEQ ID NO: 1 and consisting of 11 or less amino acid residues.

2. A pharmaceutical composition for treating or preventing cancer, comprising the peptide according to claim 1 .

3. The pharmaceutical composition according to claim 2 , wherein the composition is in the form of a vaccine.

4. The pharmaceutical composition according to claim 3 , wherein the peptide can bind to one or more types of HLA molecules.

5. An immunity inducer, comprising the peptide according to claim 1 .

6. The immunity inducer according to claim 5 , wherein the inducer is for inducing a cytotoxic T cell.

7. The immunity inducer according to claim 6 , wherein the peptide can bind to one or more types of HLA molecules.

8. A method for producing an antigen-presenting cell having a CTL-inducing activity, comprising a step of contacting the peptide according to claim 1 with an antigen-presenting cell in vitro.

9. A method for treating or preventing cancer in a subject, comprising a step of administrating to the subject a peptide comprising 8 or more consecutive amino acid residues in an amino acid sequence of SEQ ID NO: 1 and consisting of 11 or less amino acid residues.

Assignments (18)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 12, 2023
From: CYTLIMIC INC.
To: NEC CORPORATION
Reel/Frame 062357/0203 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPLICATION NUMBER 15556954 AND ASSIGNEE STREET ADDRESS PREVIOUSLY RECORDED ON REEL 043905 FRAME 0154. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 22, 2018
From: YAMAGUCHI UNIVERSITY
To: NEC CORPORATION
Reel/Frame 045107/0393 →
CORRECTIVE ASSIGNMENT TO CORRECT THE APPLICATION NUMBER 15/556,954 PREVIOUSLY RECORDED ON REEL 043904 FRAME 0948. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 22, 2018
From: MIYAKAWA, TOMOYA
To: NEC CORPORATION
Reel/Frame 045106/0456 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPLICATION NUMBER 15556954 PREVIOUSLY RECORDED ON REEL 043905 FRAME 0025. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 22, 2018
From: OKA, MASAAKI; HAZAMA, SHOICHI; TAMADA, KOJI
To: YAMAGUCHI UNIVERSITY
Reel/Frame 045106/0849 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPLICATION NUMBER 15556954 PREVIOUSLY RECORDED ON REEL 043905 FRAME 0110. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 22, 2018
From: UDAKA, KEIKO
To: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY
Reel/Frame 045106/0889 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPLICATION NUMBER 15556954 PREVIOUSLY RECORDED ON REEL 043905 FRAME 0230. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 22, 2018
From: NEC CORPORATION
To: CYTLIMIC INC.
Reel/Frame 045107/0477 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPLICATION NUMBER 15556954 PREVIOUSLY RECORDED ON REEL 043905 FRAME 0186. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jan 22, 2018
From: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY
To: NEC CORPORATION
Reel/Frame 045108/0190 →
CORRECTIVE ASSIGNMENT TO CORRECT THE APPLICATION NUMBER 15556954 PREVIOUSLY RECORDED ON REEL 043905 FRAME 0186. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 23, 2017
From: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY
To: NEC CORPORATION
Reel/Frame 044271/0697 →
CORRECTIVE ASSIGNMENT TO CORRECT THE APPLICATION NUMBER 15556954 PREVIOUSLY RECORDED ON REEL 043905 FRAME 0230. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 23, 2017
From: NEC CORPORATION
To: CYTLIMIC INC.
Reel/Frame 044271/0874 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPL. NO 15/556,954 PREVIOUSLY RECORDED AT REEL: 043904 FRAME: 0948. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 23, 2017
From: MIYAKAWA, TOMOYA
To: NEC CORPORATION
Reel/Frame 044734/0345 →
CORRECTIVE ASSIGNMENT TO CORRECT THE INCORRECT APPL. NO. 15/556,954 PREVIOUSLY RECORDED AT REEL: 043905 FRAME: 0110. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 23, 2017
From: UDAKA, KEIKO
To: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY
Reel/Frame 044734/0494 →
CORRECTIVE ASSIGNMENT TO CORRECT THE APPLICATION NUMBER 15556954 AND ASSIGNEE STREET ADDRESS PREVIOUSLY RECORDED ON REEL 043905 FRAME 0154. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 23, 2017
From: YAMAGUCHI UNIVERSITY
To: NEC CORPORATION
Reel/Frame 044271/0640 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 19, 2017
From: UDAKA, KEIKO
To: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY
Reel/Frame 043905/0110 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 19, 2017
From: OKA, MASAAKI; HAZAMA, SHOICHI; TAMADA, KOJI
To: YAMAGUCHI UNIVERSITY
Reel/Frame 043905/0025 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 19, 2017
From: YAMAGUCHI UNIVERSITY
To: NEC CORPORATION
Reel/Frame 043905/0154 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 19, 2017
From: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY
To: NEC CORPORATION
Reel/Frame 043905/0186 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 19, 2017
From: NEC CORPORATION
To: CYTLIMIC INC.
Reel/Frame 043905/0230 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 19, 2017
From: MIYAKAWA, TOMOYA
To: NEC CORPORATION
Reel/Frame 043904/0948 →
Priority Claims (1)
JP 2015-046463 · Mar 9, 2015 · national
Continuity (1)
Related Publication 20180105567A1 · Apr 19, 2018