IP Library Granted Patent US 10,981,171
Granted Patent B2
US 10,981,171 · App. 15/783,659 · Granted Apr 20, 2021

Roughly cylindrical sample containers having multiple reservoirs therein and being adapted for acoustic ejections

Inventor: Richard N. Ellson (Palo Alto, CA)
Assignee: Labcyte Inc.
B01L3/50857B01L3/50855B01J2219/00313B01J2219/00319B01J2219/00362B01L3/0244B01L3/0268B01L2400/0436
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Quick Facts
Patent No.
US 10,981,171
App. No.
15/783,659
Granted
Apr 20, 2021
Kind
B2
Abstract

Provided herein is generally tubular container, preferably including a plurality of reservoirs defined therein. The container can be adapted for acoustic ejection of a fluid disposed within at least one of the reservoirs of the plurality of reservoirs. Alternatively, the container can be adapted for extraction of a fluid disposed within at least one of the reservoirs of the plurality of reservoirs using a non-acoustic liquid handling method.

Claims (20)

1. A method comprising extracting a fluid from a generally tubular container including a plurality of reservoirs defined therein, wherein the fluid is disposed within at least one of the reservoirs of the plurality of reservoirs.

2. The method of claim 1 , wherein a plurality of fluids are respectively disposed with the reservoirs of the plurality of reservoirs, and wherein the plurality of fluids are selected from a group consisting of: different samples from a same patient, different fractions of a sample from a patient, and different concentrations of a same compound, chemical, or drug.

3. The method of claim 2 , wherein the reservoirs isolate the plurality of fluids from one another.

4. The method of claim 1 , wherein extracting the fluid from the generally tubular container comprises acoustically ejecting the fluid from the generally tubular container.

5. The method of claim 1 , wherein extracting the fluid from the generally tubular container comprises extracting the fluid using one or more of: a pipette, capillary, or pin tool.

6. The method of claim 1 , wherein the generally tubular container comprises four reservoirs and wherein extracting the fluid from the generally tubular container comprises extracting the fluid from one of the four reservoirs.

7. The method of claim 6 , wherein each of the four reservoirs of the plurality of reservoirs has a cross section that is circular.

8. The method of claim 1 , wherein at least one reservoir of the plurality of reservoirs has a cross section that is circular, rectangular, square, triangular, pentagonal, or hexagonal.

9. The method of claim 1 , wherein a cross section of at least one reservoir of the plurality of reservoirs varies along a major axis of the at least one reservoir.

10. The method of claim 9 , wherein the at least one reservoir is tapered such that a cross-section of a first end of the at least one reservoir is smaller than a second end of the at least one reservoir.

11. The method of claim 1 , wherein each reservoir of the plurality of reservoirs are acoustically distinguishable from one another and wherein the method further comprises acoustically identifying a reservoir of the plurality of reservoirs prior to extracting the fluid from the reservoir.

12. The method of claim 11 , wherein each reservoir of the plurality of reservoirs are acoustically distinguishable from one another due to the generally tubular container having a different thickness beneath each respective reservoir.

13. The method of claim 1 , wherein the generally tubular container comprises at least one lid and wherein the method further comprises removing the at least one lid prior to extracting the fluid from the reservoir.

14. The method of claim 1 , wherein the method further comprises re-lidding the generally tubular container after extracting the fluid from the reservoir.

15. The method of claim 1 , wherein the generally tubular container is stacked with at least one other generally tubular container and wherein the method further comprises de- stacking the generally tubular container prior to extracting the fluid from the reservoir.

16. The method of claim 15 , wherein the method further comprises re-stacking the generally tubular container with the at least one other generally tubular container after extracting the fluid from the reservoir.

17. A method comprising extracting a fluid from a generally tubular container including a plurality of reservoirs defined therein, a cross-section of the generally tubular container being generally circular.

18. A method comprising retrieving, as a group, a stacked plurality of generally tubular containers, at least one of the generally tubular containers including a plurality of reservoirs defined therein.

19. The method of claim 18 , wherein the method further comprises extracting a fluid from at least one of the plurality of reservoirs defined in the at least one generally tubular containers, wherein extracting the fluid from the generally tubular container comprises acoustically ejecting the fluid from the generally tubular container.

20. The method of claim 19 , wherein each reservoir of the plurality of reservoirs are acoustically distinguishable from one another and wherein the method further comprises acoustically identifying a reservoir of the plurality of reservoirs prior to extracting the fluid from the reservoir.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2018
From: ELLSON, RICHARD N.
To: LABCYTE INC.
Reel/Frame 045565/0953 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 28, 2018
From: ELLSON, RICHARD N
To: LABCYTE INC.
Reel/Frame 045070/0853 →
Continuity (3)
Continuation 14595063 · Jan 12, 2015
Provisional Application 61927878 · Jan 15, 2014
Related Publication 20180169651A1 · Jun 21, 2018