Granted Patent
B2
US 10,383,977 · App. 15/877,586 · Granted Aug 20, 2019
Cardiovascular prostheses
Assignee:
CorMatrix Cardiovascular, Inc
A61L27/3633A61F2/0095A61F2/06A61K31/4418A61L27/34A61L27/3834A61L27/507A61L27/54A61L27/58A61F2210/0004A61F2250/0067A61L2300/414A61L2430/20
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Abstract
Polymeric grafts for treating damaged biological tissue that are formed from poly(glycerol sebacate) (PGS). The PGS grafts preferably comprise a bioactive agent comprising anti-inflammatory corticosteroids, anti-oxidants, anti-thrombotic agents and anti-platelet agents. The PGS grafts can also comprise a HMG-CoA reductase inhibitor.
Claims (2)
1. A prosthesis for treating damaged cardiovascular tissue, comprising:
a sheet member consisting of an ECM-mimicking composition and a pharmacological agent, said ECM-mimicking composition consisting of poly(glycerol sebacate), said pharmacological agent consisting of a HMG-CoA reductase inhibitor consisting of cerivastatin.
Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 12, 2025
From: CORMATRIX CARDIOVASCULAR, INC.
To: CORVIVO CARDIOVASCULAR, INC.
Reel/Frame 070482/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Feb 8, 2018
From: MATHENY, ROBERT G
To: CORMATRIX CARDIOVASCULAR, INC
Reel/Frame 044868/0888 →
Continuity (3)
Cited By (1)