IP Library Patent Application 16010995
Patent Application
App. No. 16/010,995

USE OF AN OLEOGEL CONTAINING TRITERPENE FOR HEALING WOUNDS

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Quick Facts
Patent No.
US None
App. No.
16/010,995
Filed
Jun 18, 2018
Art Unit
1616
USPC
424/400
Abstract

An oleogel comprising a non-polar liquid and a powder containing triterpene is provided as an oleogel that may be used for healing wounds.

Claims (17)

1 . A method for enhancing the rate of reepithelialization of a wound, comprising administering to the wound an oleogel comprising a triterpene fraction, wherein the triterpene fraction comprises betulin.

2 . The method of claim 1 , wherein the triterpene fraction comprises between 1 weight-percent and 20 weight-percent of the oleogel.

3 . The method of claim 2 , wherein the triterpene fraction comprises between 6 weight-percent and 12 weight-percent of the oleogel.

4 . The method of claim 1 , wherein the fraction of betulin in the triterpene fraction is greater than 60 weight-percent.

5 . The method of claim 1 , wherein the fraction of betulin in the triterpene fraction is greater than 80 weight-percent.

6 . The method of claim 1 , wherein the triterpene fraction further comprises lupeol.

7 . The method of claim 6 , wherein the joint fraction of betulin and lupeol in the triterpene fraction is greater than 80 weight-percent in the triterpene fraction.

8 . The method of claim 1 , wherein the joint fraction of betulin and lupeol in the triterpene fraction is greater than 85 weight-percent in the triterpene fraction.

9 . The method of claim 1 , wherein the oleogel further comprises a nonpolar liquid.

10 . The method of claim 9 , wherein the nonpolar liquid is a plant, animal, mineral, or synthetic oil.

11 . The method of claim 10 , wherein the plant oil is a vegetable oil which is selected from one of the following: sunflower oil, olive oil, avocado oil, and almond oil.

12 . The method of claim 11 , wherein the nonpolar liquid consists of sunflower oil.

13 . The method of claim 9 , wherein the nonpolar liquid fraction comprises between 80 weight-percent and 99 weight-percent in relation to the total weight of the oleogel, and wherein the triterpene fraction comprises between 1 weight-percent and 20 weight-percent in relation to the total weight of the oleogel.

14 . The method of claim 1 , wherein the oleogel further comprises betulinic acid, oleanolic acid, and erythrodiol.

15 . The method of claim 1 , wherein the method results in complete healing of the wound.

16 . A method for healing a wound caused by a skin disease, comprising administering to the wound an oleogel comprising a triterpene fraction, wherein the triterpene fraction comprises betulin.

17 . A method for healing a wound caused by a therapeutic intervention, comprising administering to the wound an oleogel comprising a triterpene fraction, wherein the triterpene fraction comprises betulin.

Assignments (5)
MERGER Recorded Jan 12, 2024
From: AMRYT RESEARCH LIMITED
To: AMRYT PHARMACEUTICALS DESIGNATED ACTIVITY COMPANY
Reel/Frame 066110/0568 →
RELEASE OF SECURITY INTEREST Recorded Feb 23, 2022
From: CANTOR FITZGERALD SECURITIES, AS ADMINISTRATIVE AGENT
To: AEGERION PHARMACEUTICALS, INC.; AMRYT RESEARCH LIMITED
Reel/Frame 059074/0604 →
SECURITY INTEREST Recorded Sep 24, 2019
From: AMRYT RESEARCH LIMITED
To: CANTOR FITZGERALD SECURITIES, AS ADMINISTRATIVE AGENT
Reel/Frame 050478/0347 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 4, 2018
From: SCHEFFLER, ARMIN
To: BIRKEN AG
Reel/Frame 047669/0569 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 4, 2018
From: BIRKEN AG
To: AMRYT RESEARCH LIMITED
Reel/Frame 047669/0580 →