Reduced-pressure treatment and debridement systems and methods
A reduced-pressure treatment system for debriding a treatment area of a tissue site and applying reduced pressure is disclosed. The reduced-pressure treatment system includes a hydrogel having a blocked acid debriding agent. The hydrogel is adapted to cover the treatment area and enhance autolytic debridement at the treatment area. The reduced-pressure treatment system includes a manifold that is adapted to cover the hydrogel and distribute reduced pressure to the tissue site. The reduce-pressure treatment system also includes a sealing drape for forming a fluid seal over the tissue site and manifold. Other systems, methods, and dressings are presented.
1. A reduced-pressure treatment system for debriding a treatment area of a tissue site, the system comprising:
a porous hydrophilic foam adapted to cover the treatment area;
a blocked acid debriding agent applied to the porous hydrophilic foam, wherein the blocked acid debriding agent comprises an alpha hydroxy acid and a blocking material;
a manifold adapted to cover the porous hydrophilic foam and distribute reduced pressure to the tissue site; and
a sealing drape for placing over the tissue site and manifold, the sealing drape adapted to form a fluid seal over the tissue site and manifold.
2. The reduced-pressure treatment system of claim 1 , further comprising a reduced-pressure interface for delivering reduced pressure to the manifold.
3. The reduced-pressure treatment system of claim 1 , wherein the blocked acid debriding agent comprises lactic acid and an arginine group.
4. The reduced-pressure treatment system of claim 1 , wherein the blocked acid debriding agent comprises glycolic acid and arginine.
5. The reduced-pressure treatment system of claim 1 , wherein the porous hydrophilic foam is adapted to soften and break apart over time in response to exposure to wound fluid.
6. The reduced-pressure treatment system of claim 5 , wherein the manifold is adapted to absorb the porous hydrophilic foam after the porous hydrophilic foam softens.
7. The reduced-pressure treatment system of claim 1 , wherein the manifold is adapted to absorb debrided necrotic tissue.
8. The reduced-pressure treatment system of claim 1 , wherein the porous hydrophilic foam is a preformed sheet.
9. The reduced-pressure treatment system of claim 1 , further comprising an intermediate foam layer between the porous hydrophilic foam and the manifold.